GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

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Volume / Contour

See the procedure group × indication combinations in this category, ranked by evidence score. Grade reflects the volume and quality of research; direction reflects what the papers conclude.

GradeScoreDirectionIndicationProcedure groupRCT & metaClinical & observationalCase reportsTotal papers
A 67.9 Supported Nasolabial fold HA filler crosslinked 99 29 32 262
B 60.9 Supported Chin augmentation HA filler crosslinked 15 7 26 76
B 60.7 Supported Midface volume loss HA filler crosslinked 31 14 14 171
B 58.4 Supported Lip augmentation HA filler crosslinked 34 22 60 234
B 58.4 Supported Tear trough / infraorbital hollow HA filler crosslinked 14 11 35 135
B 57.7 Supported Jawline contour definition HA filler crosslinked 12 3 6 77
B 57.5 Supported Lateral cheek volume HA filler crosslinked 10 12 20 125
B 56.9 Supported Forehead volume / brow HA filler crosslinked 17 14 44 183
B 56.9 Supported Temporal hollow HA filler crosslinked 8 7 15 79
B 56.7 Insufficient Temporal hollow Collagen stimulator PDLLA PLLA 1 0 0 1
B 56.6 Supported Jawline contour definition CaHA filler 6 3 2 28
B 55.1 Supported Midface volume loss PLLA filler (Sculptra) 5 3 1 25
B 54.2 Supported Nasolabial fold CaHA filler 9 3 5 22
B 53.1 Supported Hand dorsum volume loss HA filler crosslinked 12 12 8 62
B 52.8 Supported Marionette line HA filler crosslinked 2 1 0 20
B 52.5 Supported Perioral lipstick lines HA filler crosslinked 6 1 0 11
B 51.5 Insufficient Hand dorsum volume loss Adipose matrix (Renuva) 1 0 1 2
B 50.5 Supported Temporal hollow PLLA filler (Sculptra) 3 0 2 13
C 47.0 Supported Buttock contour PLLA filler (Sculptra) 2 0 3 12
C 46.0 Insufficient Chin augmentation CaHA filler 0 1 0 8
C 45.7 Supported Midface volume loss Collagen stimulator PDLLA PLLA 1 0 0 4
C 41.0 Supported Hand dorsum volume loss CaHA filler 3 7 0 25
C 40.4 Supported Nasolabial fold Pdo PCL PLLA thread lifting 0 2 4 15
C 40.2 Insufficient Buttock contour CaHA filler 1 1 0 7
C 37.1 Mixed Prejowl sulcus HA filler crosslinked 1 0 1 11
D 34.5 Insufficient Ear lobe volume HA filler crosslinked 0 0 0 6
D 34.3 Insufficient Nasolabial fold PCL filler 0 0 0 1
D 26.2 Insufficient Hand dorsum volume loss PLLA filler (Sculptra) 0 3 1 14
D 25.4 Insufficient Neck horizontal lines Collagen stimulator PDLLA PLLA 0 0 0 1
D 25.4 Insufficient Neck horizontal lines CaHA filler 0 0 2 1
D 25.0 Insufficient Lateral cheek volume Collagen stimulator PDLLA PLLA 0 0 0 6
F 13.2 Insufficient Body localized volume defect Adipose matrix (Renuva) 0 0 0 2
F 0.0 Insufficient Neck horizontal lines Acellular dermal matrix ECM skinbooster 0 0 0 0
F 0.0 Insufficient Neck horizontal lines HA glycerol skinbooster 0 0 0 0
F 0.0 Insufficient Hand dorsum volume loss HA skin booster 0 0 0 0
F 0.0 Insufficient Neck horizontal lines HA skin booster 0 0 0 0
F 0.0 Insufficient Midface volume loss Hybrid dual HA skinbooster volume 0 0 0 0
F 0.0 Insufficient Neck horizontal lines Microdosed botulinum for skin 0 0 0 0
F 0.0 Insufficient Jawline contour definition PCL filler 0 0 0 0
F 0.0 Insufficient Marionette line PCL filler 0 0 0 0
F 0.0 Insufficient Midface volume loss PCL filler 0 0 0 0
F 0.0 Insufficient Neck horizontal lines PLLA filler (Sculptra) 0 0 0 0
F 0.0 Insufficient Neck horizontal lines PN PDRN injection with HA 0 0 0 0