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Nasolabial fold
Compare the procedure groups used for this indication, ranked by evidence grade. Each grade comes from an expert read of the actual studies (design, quality, on-topic relevance); direction reflects what those studies conclude.
| Grade | Direction | Procedure group | RCT & meta | Clinical & observational | Case reports | Total papers |
|---|---|---|---|---|---|---|
| A | Supported | HA filler crosslinked | 99 | 29 | 32 | 262 |
| A | Supported | CaHA filler | 9 | 3 | 5 | 22 |
| D | Limited | Pdo PCL PLLA thread lifting | 0 | 2 | 4 | 15 |
| D | Insufficient | PCL filler | 0 | 0 | 0 | 1 |