PLLA filler (Sculptra) evidence for Temporal hollow

Abstract summary (English) BACKGROUND: As the popularity of non-hyaluronic acid (HA) injectables such as biostimulators rise in medical aesthetics, so have the rates of complications related to these injectables, including that of iatrogenic visual loss from vascular occlusion. METHODS: The authors conducted a systematic review of the available literature on visual loss related to the most widely used biostimulator injectables including...

Journal Article, Systematic Review, Review

Abstract summary (English) BACKGROUND: Facial aging leads to cosmetically unappealing volume loss in the temples. We systematically reviewed the available literature regarding nonsurgical temporal volumization with injectable fillers. METHODS: On Sept 16, 2024, Medline, Scopus, Embase, and Cochrane databases were queried with relevant terms for all articles describing temporal volumization with injectable fillers, including those with...

Journal Article, Systematic Review

Abstract summary (English) BACKGROUND: Poly- l -lactic acid (PLLA-SCA) can be used to improve the aesthetics of the temporal fossae but is usually only deposited within the visible area of the temporal hollows. However, extending the treatment area posterior to the hairline may provide a greater lifting effect. OBJECTIVES: Assess the efficacy and safety of 2 techniques (traditional vs extended) of injecting PLLA-SCA for aesthetic improvement...

Journal Article, Randomized Controlled Trial, Comparative Study

Abstract summary (English) PURPOSE: To review evidence on ocular complications of injectable soft tissue fillers, identify features associated with risk for vision loss, and assess the efficacy and safety of reported treatments. METHODS: Literature search of the PubMed database was last conducted in May 2024. Articles were limited to English-language original research describing ocular complications of soft tissue fillers.

Journal Article, Review

Abstract summary (English) Injectable fillers have become a prevalent means of facial rejuvenation and volume expansion. While typically well tolerated, serious complications have been reported. The authors present a case in which an otherwise healthy female with a history of multiple filler injections including poly-L-lactic acid, developed 3 weeks of neuropathic pain in the left temporal fossa following injection.

Case Reports, Journal Article

Abstract summary (English) BACKGROUND: Temple hollowing represents a prevalent aesthetic concern traditionally addressed with autologous fat grafting or hyaluronic acid fillers. Poly-L-lactic acid (PLLA) offers gradual, collagen-mediated volumization and is increasingly utilized for soft-tissue augmentation. Nevertheless, to date, no approved study has evaluated its use for temporal augmentation.

Journal Article

Abstract summary (English) BACKGROUND: Poly-l-lactic acid (PLLA) is an injectable biostimulatory filler used for restoring facial fat volume loss. OBJECTIVE: To evaluate the safety and efficacy of injectable PLLA injections for volume loss in the temples using dual plane injections. Assessments included live ratings and ratings of standardized pictures and ultrasound imaging at weeks 4, 8, 12, and 16 by a trained evaluator.

Journal Article

Abstract summary (English) INTRODUCTION: The temporal region is emblematic and challenging due to its structural and volumetric changes during aging, which significantly affect facial aesthetics. Despite the importance of addressing temporal aging, many injectors hesitate due to the region's anatomical complexity and risk of complications. This consensus aimed to provide expert guidance on the safest and most effective treatment strategies...

Journal Article

Abstract summary (English) OBJECTIVES: When poly-L-lactic acid (PLLA) was first introduced (marketed as New-Fill), incorrect injection technique was largely responsible for the manifestation of device-related adverse events in the form of subcutaneous papules and areas of induration. Now marketed as Sculptra, widespread clinical experience with injectable PLLA has resulted in a wealth of information on product reconstitution and correct...

Case Reports, Journal Article, Research Support, Non-U.S. Gov't

Abstract summary (English) The next three articles in this issue take a unique approach to discussing volumetric restoration. Robert Glasgold has provided an assessment for each facial region and five different renowned authors (TK, SPS, RF, SML, and EFW) have been asked to speak on a particular volumetric product, of which they are considered an expert, as it applies to the different regions of the face. The articles are broken into the...

Journal Article