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Midface volume loss
Compare the procedure groups used for this indication, ranked by evidence grade. Each grade comes from an expert read of the actual studies (design, quality, on-topic relevance); direction reflects what those studies conclude.
| Grade | Direction | Procedure group | RCT & meta | Clinical & observational | Case reports | Total papers |
|---|---|---|---|---|---|---|
| A | Supported | HA filler crosslinked | 31 | 14 | 14 | 171 |
| A | Supported | PLLA filler (Sculptra) | 5 | 3 | 1 | 25 |
| C | Supported | Collagen stimulator PDLLA PLLA | 1 | 0 | 0 | 4 |
| F | Insufficient | Hybrid dual HA skinbooster volume | 0 | 0 | 0 | 0 |
| F | Insufficient | PCL filler | 0 | 0 | 0 | 0 |