Collagen stimulator PDLLA PLLA evidence for Midface volume loss

Abstract summary (English) BACKGROUND: Injectable Poly-L-lactic acid (PLLA) is effective in restoring mid-face volume and is widely used treating the nasolabial fold (NLF). This study aimed to compare the safety and efficacy of a novel PDLLA based product (PDLLA + non-cross-linked HA; Poly-D, L-lactic acid + hyaluronic acid) with that of a commonly used PLLA for NLF correction. METHODS: In this multi-center, randomized, split-face,...

Journal Article, Multicenter Study, Randomized Controlled Trial, Comparative Study

Abstract summary (English) Orbital floor fractures, often combined with zygomatic fractures, are common fractures of the midface. Surgery of orbital fractures is done to free incarcerated or prolapsed orbital tissue and to restore the anatomic skeletal size of the orbit. Lyodura was a standard for the reconstruction of the orbital floor until cases of Creutzfeldt-Jakob disease were reported, so that polydioxanone (PDS) is widely used today.

Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) INTRODUCTION: The combination of hyaluronic acid (HA) fillers and polydioxanone (PDO) thread lifting is gaining popularity for mid-face rejuvenation, especially among the Asian population. Despite the common use of these techniques, there is a paucity of long-term studies assessing their combined efficacy and safety. This study aims to evaluate the efficacy and safety of combined HA filler and PDO thread treatment...

Journal Article, Clinical Trial

Abstract summary (English) BACKGROUND: Traditional facial aging surgeries have risks and extended recovery times, leading to a demand for minimally invasive alternatives. PDO (polydioxanone) threads, which are absorbable sutures that stimulate collagen production and tissue contraction, offer improved aesthetic outcomes. This paper evaluates the combined use of PDO thread mid-cheek lift and lower blepharoplasty for facial rejuvenation.

Journal Article, Comparative Study

Abstract summary (English) BACKGROUND: The use of polydioxanone thread has grown substantially for facial soft-tissue repositioning and collagen biostimulation, with a well-established safety profile and favorable tissue integration. AIMS: To describe the reverse knot technique, a novel method for the implantation of polydioxanone suspension threads. PATIENTS/METHODS: We present an original polydioxanone thread-lifting technique designed...

Journal Article

Abstract summary (English) BACKGROUND: Thread lifting is a minimally invasive procedure using absorbable sutures like polydioxanone (PDO) to provide immediate lifting and stimulate collagen for long-term skin rejuvenation. This prospective study evaluates the safety and efficacy of Croquis® Barbed Cutting PDO threads, featuring a unique 3D bi-directional barb design, in enhancing facial lifting outcomes. METHODS: Thirty participants with...

Journal Article

Abstract summary (English) BACKGROUND: The popularity of dermal fillers in aesthetic procedures has led to an increase in complications, including nodules that can be challenging to diagnose and treat. The role of ultrasound as a noninvasive diagnostic tool across different fillers remains underexplored. OBJECTIVE: To investigate the clinical features and ultrasound characteristics of dermal filler nodules.

Journal Article

Abstract summary (English) BACKGROUND: Minimally invasive aesthetic procedures, such as the use of polydioxanone (PDO) threads, are increasingly popular for facial rejuvenation. OBJECTIVES: This study investigates the impact of the number of PDO threads on tissue displacement, volume changes, and patient satisfaction. METHODS: This randomized controlled trial involved 22 patients seeking facial lifting using PDO threads.

Journal Article

Abstract summary (English) The clinical application of polydioxanone (PDO) threads, traditionally utilized for tissue lifting, is now being explored for its volumizing effects in midface rejuvenation. The novel approach involves employing PDO volumizing threads to achieve physical augmentation akin to a "solid filler." The study introduces a more convenient insertion method for these threads, prioritizing ease and efficacy. Clinical cases...

Journal Article