HA filler crosslinked evidence for Temporal hollow

Abstract summary (English) BACKGROUND AND AIM: With age, temple depressions appear due to age-related atrophy of fatty tissue, leading to a prominent cheekbone and lateral rim of the eye socket. Hyaluronic acid fillers have become very popular in the temple area due to their simple procedure and reliable results. The present study was conducted with the aim of determining the effectiveness of filler injection between the superficial and deep...

Journal Article, Meta-Analysis, Systematic Review

Abstract summary (English) BACKGROUND: As the popularity of non-hyaluronic acid (HA) injectables such as biostimulators rise in medical aesthetics, so have the rates of complications related to these injectables, including that of iatrogenic visual loss from vascular occlusion. METHODS: The authors conducted a systematic review of the available literature on visual loss related to the most widely used biostimulator injectables including...

Journal Article, Systematic Review, Review

Abstract summary (English) BACKGROUND: Facial aging leads to cosmetically unappealing volume loss in the temples. We systematically reviewed the available literature regarding nonsurgical temporal volumization with injectable fillers. METHODS: On Sept 16, 2024, Medline, Scopus, Embase, and Cochrane databases were queried with relevant terms for all articles describing temporal volumization with injectable fillers, including those with...

Journal Article, Systematic Review

Abstract summary (English) BACKGROUND: Temple hollowing is characterized by a reduction of volume in the temporal fossa, which can result in a skeletonized look and contribute to an aged appearance. This study aimed to evaluate the safety and effectiveness of VYC-20L injectable gel to improve temple hollowing. METHODS: Adults with minimal, moderate, or severe temple hollows were randomized 2:1 to receive VYC-20L or no treatment.

Journal Article, Randomized Controlled Trial, Multicenter Study

Abstract summary (English) BACKGROUND: Poly- l -lactic acid (PLLA-SCA) can be used to improve the aesthetics of the temporal fossae but is usually only deposited within the visible area of the temporal hollows. However, extending the treatment area posterior to the hairline may provide a greater lifting effect. OBJECTIVES: Assess the efficacy and safety of 2 techniques (traditional vs extended) of injecting PLLA-SCA for aesthetic improvement...

Journal Article, Randomized Controlled Trial, Comparative Study

Abstract summary (English) BACKGROUND: Hyaluronic acid-based fillers have an immediate volumizing effect for the treatment of dermal contour deformities and to smooth dermal depressions formed by the loss of volume. A previous study on 2016-2018 has shown the efficacy and safety of the HA-based filler ART FILLER® Volume on the midface only, but not in a comparative manner. METHODS: In this context, an 18 months prospective randomized...

Randomized Controlled Trial, Journal Article, Equivalence Trial

Abstract summary (English) BACKGROUND: Treatment of a sunken appearance of the temporal region using injectable fillers is a popular procedure. The temporal fossa has very complex anatomy due to multiple vessels running in the different tissue layers. A severe complication in the form of non-thrombotic pulmonary embolism (NTPE) can occur as a result of an inadvertent injection in the middle temporal vein (MTV) while performing temporal fossa...

Journal Article, Systematic Review

Abstract summary (English) Objective: The aim of the present study is to compare the temporal surface volume coefficient obtained in the cadaveric model from subdermal and supraperiosteal injections to the clinical setting when treating temporal hollowing. Material and Methods: A total of 36 subjects were included in this investigation, 17 patients (16 females, 1 male; 46.3 ± 8.9 years; 25.5 ± 2.8 kg/m2) and 19 cadaveric specimens (11...

Journal Article, Randomized Controlled Trial, Validation Study

Abstract summary (English) BACKGROUND: Facial aging is characterized by volume loss and progressive hollowing of temples and cheeks. Biodegradable filler materials are preferred over nonabsorbable materials; of these, hyaluronic acid (HA) fillers are the most often used because of their favorable effectiveness and safety profile. OBJECTIVE: To confirm the safety and effectiveness of Cohesive Polydensified Matrix (CPM)-HA26 gel in the...

Clinical Trial, Journal Article, Multicenter Study

Abstract summary (English) Objective: To study the safety, efficacy, optimal volume, and longevity of an injectable hyaluronic acid (HA) gel dermal filler to treat facial temporal fossa fat loss. Methods and materials: This open-label, single-site, 12-month study used 20 mg/mL HA gel to correct volume loss in both temples in 30 subjects. Touch-ups were allowed at week 2.

Clinical Trial, Journal Article