GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Volume / Contour · Lateral cheek volume

Collagen stimulator PDLLA PLLA evidence for Lateral cheek volume

D 25.0 / 100 Insufficient 0 RCT/meta · 0 clinical/observational · 0 case · 6 total
Insufficient evidence

There is not yet enough PubMed evidence for this combination. The procedure exists, but research on this indication may be scarce.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2024 Last 5 years 50% Positive results 33% Korea/Asia 1

Known in Korea as

쥬베룩쥬베룩 볼륨울트라콜 100울트라콜 200

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier_other Facial Retaining Structures are Not True Ligaments: Clinical Application. The Journal of craniofacial surgery · 2026 · PMID 41855112

Abstract summary (English) BACKGROUND: The so-called facial retaining ligaments have long been described in aesthetic anatomy; however, their histologic characteristics and mechanical behavior differ from those of true ligaments found in the appendicular skeleton. This study aims to clarify the structural and functional nature of these fibrous retaining structures and discuss their clinical implications for soft-tissue filler and collagen...

Journal Article

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tier_other Regenerative Synergy in Facial Rejuvenation: A Pilot Clinical Study of Polydioxanone Microspheres (Ultra V® UltraCol 200), Organic Silicon, and Adipostructuring. Cureus · 2026 · PMID 41835036

Abstract summary (English) Background Dermal fillers used with minimally invasive techniques have currently achieved an important role in regenerative medicine and in alleviating skin damage over the years. Objectives To evaluate clinical results after the use of the Polydioxanone Collagen Biostimulator Ultra V® UltraCol 200 (Ultracol), commonly referred to as PDO microspheres, with the addition of organic silicon to enhance Ultracol...

Journal Article

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tier_other Exploring the Safety and Satisfaction of Patients Injected With Collagen Biostimulators-A Prospective Investigation Into Injectable Poly-l-Lactic Acid (PLLA). Journal of cosmetic dermatology · 2024 · PMID 39663956

Abstract summary (English) BACKGROUND: Esthetic medicine has shifted significantly toward non-surgical procedures, with the collagen biostimulator poly-l-lactic acid (PLLA) becoming increasingly popular for facial rejuvenation. However, the safety and patient satisfaction associated with PLLA facial treatments remain largely unexplored. OBJECTIVE: This study aimed to evaluate the safety profile of PLLA treatment and assess patient mid- and...

Journal Article

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tier_other Significance of biodegradable implants in case of midfacial fractures. Biomedizinische Technik. Biomedical engineering · 2002 · PMID 12451904

Abstract summary (English) The purpose of this prospective clinical study was to evaluate new resorbable implants for bone fixation. The plates and screws are made of poly (D, L)lactide (PDLLA). Bioresorbable osteosynthesis and fixation (ResorbX) has been applied in 22 patients.

Journal Article

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tier_other [Tissue reaction and degradation of super-high molecular weight poly D, L-lactic acid mini-plates and screws: an animal experiment]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 1999 · PMID 12539328

Abstract summary (English) OBJECTIVE: To investigate the tissue reaction and degradation processes of the super-high molecular weight(Mv = 6.0 x 10(5) kD) poly D, L-lactic acid(PDLLA) mini-plates and screws through the internal fixation for zygomatic arch fracture. METHODS: It was carried out by the self-contrast study method and comparing with the titanium mini-plates and screws. RESULTS: There was no side-effects on bone healing.

Journal Article, Research Support, Non-U.S. Gov't

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tier_other [Internal fixation for zygomatic arch fracture with super-high molecular weight poly D, L-lactic acid mini-plates and screws: a study in dogs]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 1999 · PMID 12539327

Abstract summary (English) OBJECTIVE: To investigate the internal fixation effects of super high molecular weight (Mv = 6.0 x 10(5) kD) poly D, L-lactic acid(PDLLA) mini-plates and screws. METHODS: 10 dogs were utilized in this experiment with the self-contrast study method, comparing with the titanium mini-plates and screws. RESULTS: The mechanical properties of the PDLLA mini-plates and screws appeared to be sufficient to enable undisturbed...

Journal Article, Research Support, Non-U.S. Gov't

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Suggested interpretation

Needs further review

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