GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

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Pigment

See the procedure group × indication combinations in this category, ranked by evidence score. Grade reflects the volume and quality of research; direction reflects what the papers conclude.

GradeScoreDirectionIndicationProcedure groupRCT & metaClinical & observationalCase reportsTotal papers
A 72.5 Supported PIH Picosecond laser pigment 48 12 25 126
A 69.5 Supported Melasma (epidermal) Picosecond laser pigment 23 7 7 58
A 68.5 Supported Melasma (mixed / dermal) Picosecond laser pigment 8 4 0 15
A 66.7 Supported Nevus of Ota Picosecond laser pigment 7 1 9 27
A 66.4 Supported PIH Laser toning qswitched or picosecond 60 35 51 198
A 65.2 Supported Melasma (epidermal) Laser toning qswitched or picosecond 39 20 13 125
B 63.1 Supported Solar lentigo / sunspot Picosecond laser pigment 6 3 9 23
B 62.2 Supported Freckles / ephelides Picosecond laser pigment 4 1 2 7
B 61.4 Supported PIH Chemical peel 44 32 21 199
B 60.8 Supported Melasma (epidermal) Fractional picosecond resurfacing 7 2 0 24
B 59.9 Supported Melasma (mixed / dermal) Laser toning qswitched or picosecond 11 9 5 40
B 59.0 Supported Melasma (epidermal) Chemical peel 24 22 8 121
B 58.8 Supported Solar lentigo / sunspot Laser toning qswitched or picosecond 15 3 6 32
B 58.5 Supported Nevus of Ota Laser toning qswitched or picosecond 10 12 6 64
B 58.2 Supported Solar lentigo / sunspot Vascular pigment laser 532 1064 4 3 2 19
B 57.6 Supported Melasma (epidermal) Nonablative fractional resurfacing 5 4 1 24
B 56.9 Insufficient Solar lentigo / sunspot Fractional picosecond resurfacing 2 1 1 4
B 54.1 Supported Melasma (epidermal) Ionzyme iontophoresis sonophoresis 6 4 2 15
B 51.1 Supported Cafe-au-lait macule Laser toning qswitched or picosecond 2 4 5 15
B 50.0 Supported Solar lentigo / sunspot IPL bbl photorejuvenation 8 5 8 55
C 48.0 Supported Hori macules Laser toning qswitched or picosecond 5 2 2 16
C 45.5 Supported Poikiloderma of Civatte IPL bbl photorejuvenation 1 1 1 12
C 44.0 Supported Solar lentigo / sunspot Nonablative fractional resurfacing 1 1 2 6
C 42.9 Supported Poikiloderma of Civatte Vascular pigment laser 532 1064 0 1 0 2
C 41.2 Supported Freckles / ephelides Laser toning qswitched or picosecond 3 0 1 5
C 37.5 Supported Freckles / ephelides IPL bbl photorejuvenation 1 1 1 17
C 37.0 Insufficient Periorbital dark circle Picosecond laser pigment 0 1 0 2
D 23.9 Insufficient Seborrheic keratosis Laser toning qswitched or picosecond 0 1 0 1
F 0.0 Insufficient Melasma (epidermal) Needle free drug delivery 0 0 0 0
F 0.0 Insufficient Periorbital dark circle PN PDRN injection 0 0 0 0
F 0.0 Insufficient Periorbital dark circle PN PDRN injection with HA 0 0 0 0