Vascular pigment laser 532 1064 evidence for Solar lentigo / sunspot

Abstract summary (English) BACKGROUND: Many patients with psoriasis suffer from post-inflammatory pigmentary alteration (PIPA), which remains an unmet treatment need. Eruptive lentiginosis (EL) is a rare form of PIPA where multiple dark brown macules arise within a resolving psoriatic plaque. We present a case of a 68-year-old male with a history of chronic plaque psoriasis and prothrombin deficiency, who developed extensive EL following...

Journal Article, Systematic Review, Case Reports

Abstract summary (English) OBJECTIVE: This study aims to assess the effectiveness and safety of the 730-nm picosecond laser, the 532-nm picosecond laser, and the Q-switched 694-nm nanosecond laser in treating freckles and solar lentigines. METHODS: The randomized clinical trial included 42 participants who met the specific eligibility criteria for freckles and solar lentigines. On each participant's face, three distinct skin areas affected by...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Solar lentigines, resulting from chronic UV exposure, are early signs of photoaging and can significantly affect individuals. AIMS: This systematic review evaluates the efficacy, safety, and tolerability of treatments for solar lentigines in light of a lack of conclusive evidence regarding optimal therapy options. METHODS: A systematic search of PubMed/Medline, EMBASE, Cochrane Library, and...

Systematic Review, Journal Article

Abstract summary (English) BACKGROUND: Although post-inflammatory hyperpigmentation (PIH) is a common adverse event following laser procedures, studies evaluating its risk remain limited. OBJECTIVE: To analyze PIH risk after 532 nm Q-switched Nd:YAG laser (QSNYL) treatment for solar lentigines and examine the efficacy of triple combination cream (TCC) for its prevention. METHODS: In this single center, investigator-blinded, randomized...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND/OBJECTIVE: Laser therapy has emerged as a widely favored treatment option for solar lentigines (SL). However, a significant challenge associated with this treatment, particularly among individuals with darker skin tones, is the notable risk of postinflammatory hyperpigmentation (PIH) induction. In response to these concerns, the authors conducted a prospective, self-controlled study to comprehensively...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Q-switched (QS) Nd: YAG laser is one of the treatment options for solar lentigines (SLs). However, the incidence of post-inflammatory hyperpigmentation (PIH) is a common complication, especially in dark-complexioned skin. Isobutylamido thiazolyl resorcinol (ITR) has been reported as a preventive modality for ultraviolet B (UVB)-induced hyperpigmentation.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Solar lentigo (SL) is a benign hyperpigmented spot occurring due to ultraviolet exposure, most commonly in the elderly. We aimed to compare the safety and efficacy of trichloroacetic acid (TCA) peeling with Q-switched laser in the treatment of SLs. METHODS: This assessor-blind split-hand randomized controlled trial included 45 patients with symmetric SLs on the back of their hands referred to the...

Randomized Controlled Trial, Journal Article

Abstract summary (English) BACKGROUND: Various pigment-specific lasers can be used to treat solar lentigines. However, the most effective treatment options remain to be explored to reduce complications, such as postinflammatory hyperpigmentation, especially in dark-skinned patients. OBJECTIVES: This study aims to compare the efficacy and safety between the KTP 532-nm picosecond laser and the alexandrite 755-nm picosecond laser for the...

Journal Article, Randomized Controlled Trial

Abstract summary (English) Background and Objective: Little is known about the anti-pigmentation effects of whitening agents on solar lentigines. Epidermal growth factor (EGF) has been used as a booster for wound healing in the skin, and it has been suggested to have anti-pigmentation effects. This study aimed to evaluate the effect and safety of EGF-containing ointment for treating solar lentigines with a Q-switched (QS) 532 nm...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Whether picosecond lasers outperform Q-switched lasers in treating pigmented lesions has not been clearly evaluated. OBJECTIVE: To compare the efficacy and safety of picosecond and Q-switched lasers in treating epidermal and dermal pigmented lesions in Asians. METHODS: Eight subjects with lentigines and 6 subjects with acquired bilateral nevus of Ota-like macules were enrolled.

Clinical Trial, Phase IV, Comparative Study, Journal Article, Randomized Controlled Trial