Chemical peel evidence for Melasma (epidermal)

Abstract summary (English) BACKGROUND: Melasma is an acquired hypermelanosis. Chemical peels have been found efficacious in melasma. However, limited studies have compared the efficacy of various peels in melasma and used dermoscopy to evaluate improvement.

Journal Article, Randomized Controlled Trial, Comparative Study

Abstract summary (English) BACKGROUND: Melasma is a common chronic, relapsing pigmentary disorder that causes psychological impact. Chemical peels are a well-known therapeutic modality used for accelerating the treatment of melasma. OBJECTIVE: To review the published evidence on the efficacy and safety of chemical peels in the treatment of melasma.

Systematic Review, Journal Article

Abstract summary (English) OBJECTIVE: To observe the efficacy and safety of supramolecular salicylic acid monotherapy and supramolecular nicotinamide in the treatment of chloasma. METHODS: A total of 28 female patients with chloasma diagnosed in the dermatology outpatient department of our hospital were randomly divided into an experimental group and a control group, with 14 cases in each group. All patients were treated with 30%...

Randomized Controlled Trial, Journal Article

Abstract summary (English) BACKGROUND: Melasma is a common acquired disorder of hyperpigmentation which is difficult to treat. OBJECTIVE: We aim to evaluate the efficacy and safety of combined microneedling with trichloroacetic acid in the treatment of melasma. PATIENTS AND METHODS: Forty women with facial melasma were included and randomly classified into 2 groups.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Chemical peelings are used on a wide scale in cosmetic field including melasma treatment. They often provide clinicians with flexibility in tailoring treatments according to patient needs and satisfaction. OBJECTIVE: To evaluate safety and efficacy of chemical peeling as single agents in melasma management in patients with darker skin types.

Journal Article, Meta-Analysis, Systematic Review

Abstract summary (English) BACKGROUND: Melasma is an acquired, chronic pigmentary disorder predominantly affecting women. It may significantly affect quality of life and self-esteem due to its disfiguring appearance. Multiple treatments for melasma are available, with mixed results.

Journal Article, Systematic Review

Abstract summary (English) BACKGROUND: To study and compare the therapeutic efficacy and side effects of a 35% glycolic acid (GA) full face peel alone or in combination with a 10% or 20% trichloroacetic acid (TCA) spot peel for facial melasma. METHODS: Thirty patients with facial melasma were randomly divided into 3 equal Groups A, B, and C. Group A was treated with a 35% GA full-face peel, Group B and C with 35% GA full-face peel followed by...

Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) INTRODUCTION: Melasma is a distressing condition for both dermatologists and patients. We evaluated the effectiveness of salicylic acid (SA) peel and vitamin C mesotherapy in the treatment of melasma. MATERIALS AND METHODS: Fifty female patients were divided into two groups.

Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Melasma is a common challenging pigmentary skin disorder especially in dark-skinned females urging them to seek medical help. Many modalities of treatment are available, but none is satisfactory. OBJECTIVE: To compare safety and efficacy of combined trichloroacetic acid (TCA) (20%-25%) and Jessner's solution versus TCA (20%-25%) alone in dark patients with melasma.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Glycolic acid (GA) peel is one of the most versatile agents in the treatment of melasma. GA peeling alone or in combination with topical hypopigmenting agents has shown encouraging results. However, there is paucity of controlled trial demonstrating the efficacy of glycolic peel in conjunction with topical azelaic acid (AA).

Journal Article, Randomized Controlled Trial