Laser toning qswitched or picosecond evidence for Nevus of Ota

Abstract summary (English) BACKGROUND: The nevus of Ota is an uncommon pigmentary skin condition that causes bluish-gray pigmentation and is traditionally treated with a Q-switched laser. Emerging evidence suggests that the 755-nanometer picosecond alexandrite laser is a safe and effective therapeutic option. We sought to determine the overall effectiveness and safety profile of the 755-nanometer (nm) picosecond alexandrite laser for managing...

Journal Article, Systematic Review, Meta-Analysis

Abstract summary (English) BACKGROUND: Epidermal growth factor (EGF) may promote wound healing and decrease laser-induced postinflammatory hyperpigmentation (PIH). OBJECTIVES: To evaluate the effectiveness of an EGF-containing cream on PIH, post-laser erythema, and transepidermal water loss (TEWL) after 1,064-nm Q-Switched Nd: YAG laser treatment of Hori's nevus. METHODS: This is a split-face, double-blinded, randomized, controlled study...

Journal Article, Randomized Controlled Trial

Abstract summary (English) Nevus of Ota is cosmetically burdensome and often prompts patients to seek treatment. Lasers are commonly used in removing these lesions; however, no systemic analysis has been conducted to support a gold standard laser. To conduct a meta-analysis of the efficacy and safety of Q-switched Nd:YAG lasers (QSNL), Q-switched ruby lasers (QSRL), Q-switched alexandrite lasers (QSAL), and picosecond alexandrite lasers...

Journal Article, Meta-Analysis, Systematic Review

Abstract summary (English) BACKGROUND: Whether picosecond lasers outperform Q-switched lasers in treating pigmented lesions has not been clearly evaluated. OBJECTIVE: To compare the efficacy and safety of picosecond and Q-switched lasers in treating epidermal and dermal pigmented lesions in Asians. METHODS: Eight subjects with lentigines and 6 subjects with acquired bilateral nevus of Ota-like macules were enrolled.

Clinical Trial, Phase IV, Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) We aimed to investigate the efficacy and safety of using the 1064-nm Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser (QSNYL) for skin rejuvenation in patients with Nevus of Ota. A retrospective, randomized, split-faced, clinical study was conducted. Twenty-nine patients with unilateral moderate to severe Nevus of Ota were enrolled.

Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) Although the application of Q-switched lasers on nevus of Ota (OTA) is well demonstrated, debates about clinical option between Q-switched alexandrite laser (QSA) and Q-switched Nd:YAG laser (QSNY) still remain. This systematic review and meta-analysis estimated the overall successful rate of OTA pigment clearance and complication rate of QSA and QSNY and evaluated which laser could produce a better result. English...

Comparative Study, Journal Article, Meta-Analysis, Systematic Review

Abstract summary (English) Different types of Q-switched (QS) lasers have been used successfully to treat nevus of Ota. The purpose of this study was to compare the clinical efficacy and complication of QS alexandrite (QS Alex) laser versus QS neodymium:yttrium aluminum garnet (Nd:YAG) (QS Nd:YAG) laser for bilateral nevus of Ota. Seventeen patients with bilateral nevus of Ota were treated randomly with QS Alex in one half of face and QS...

Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Post-inflammatory hyperpigmentation (PIH) after laser treatment of Hori nevus remains problematic. Prevention and treatment of PIH have limited success. OBJECTIVE: To study the effects on hyperpigmentation using topical antibiotic alone versus combined antibiotic and betamethasone/valerate after 1064 nm Q-switched Nd:YAG laser treatment of Hori nevus.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Q-switched laser treatment for pigment disorders commonly leads to postinflammatory hyperpigmentation (PIH) in Asians. OBJECTIVES: To evaluate the effect of spot size and fluence on Q-switched alexandrite laser (QSAL) treatment for pigmentation in Asians. METHODS: Ten patients with freckles, 18 with lentigines, and 8 with acquired bilateral nevus of Ota-like macules (ABNOM) received 1 session of QSAL...

Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) OBJECTIVE: To investigate the effect of cold air cooling on the incidence of postinflammatory hyperpigmentation (PIH) after laser treatment in Asian patients. DESIGN: Randomized, controlled, split-face study. SETTING: Skin laser center of a university hospital.

Journal Article, Randomized Controlled Trial