GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Pigment · Poikiloderma of Civatte

Vascular pigment laser 532 1064 evidence for Poikiloderma of Civatte

C 42.9 / 100 Supported 0 RCT/meta · 1 clinical/observational · 0 case · 2 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2007 Last 5 years 10% Positive results 63%

Known in Korea as

더마V엑셀V엑셀브이더마V레이저엑셀V 제네시스더마V 싱글/듀얼/트리플

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Safety and Effectiveness of a New 532 nm, Long Pulse-Duration, Variable Pulse Structure Laser for Treatment of Poikiloderma of Civatte. Lasers in surgery and medicine · 2025 · PMID 39789753

Abstract summary (English) BACKGROUND: Poikiloderma of Civatte is a benign skin condition characterized by reticulate erythema and hyperpigmentation in sun-exposed areas, predominantly on the neck, cheeks, and chest. Chronic UV exposure leads to vascular proliferation and red cell extravasation resulting in hemosiderin and melanin deposition. While many light-based modalities have been utilized to treat the disorder, the significant...

Journal Article, Randomized Controlled Trial

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tier1 Application of intense pulsed light in the treatment of dermatologic disease: a systematic review. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2014 · PMID 24495252

Abstract summary (English) BACKGROUND: The Food and Drug Administration (FDA) has approved intense pulsed light (IPL) devices for the treatment of a variety of benign pigmentary and vascular lesions, but the range of disease amenable to IPL treatment continues to expand, and there are no evidence-based clinical guidelines for its use in FDA-approved and off-label indications. OBJECTIVE: To provide evidence-based recommendations to guide...

Journal Article, Systematic Review

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tier2 Treatment of poikiloderma of Civatte using intense pulsed light source: 7 years of experience. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2007 · PMID 18177401

Abstract summary (English) BACKGROUND AND OBJECTIVE: The treatment of choice of poikiloderma of Civatte should address both pigmented and vascular lesions at the same time. A broad-spectrum, noncoherent intense pulsed light (IPL) source can be used to obtain this effect. In this study, we investigated the clinical efficacy and side effects of treating this condition with IPL.

Clinical Trial, Journal Article

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tier2 Treatment of poikiloderma of Civatte with the pulsed dye laser: a series of patients with severe depigmentation. Journal of the European Academy of Dermatology and Venereology : JEADV · 2006 · PMID 17062040

Abstract summary (English) BACKGROUND: Pulsed dye laser (PDL) treatment is widely used for poikiloderma of Civatte. Some adverse events in small numbers of patients have been reported. Guidelines for treatment of poikiloderma of Civatte do not exist.

Clinical Trial, Journal Article

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tier0_review Treatment of Poikiloderma of Civatte with ablative fractional laser resurfacing: prospective study and review of the literature. Journal of drugs in dermatology : JDD · 2009 · PMID 19537378

Abstract summary (English) BACKGROUND: Previous laser treatments for Poikiloderma of Civatte (PC) (i.e., Pulsed dye, Intense Pulsed Light, KTP and Argon) are limited by side effect profiles and/or efficacy. Given the high degree of safety and efficacy of ablative fractional photothermolysis (AFP) for photoaging, we set out to assess the efficacy of PC with AFP. DESIGN: A prospective pilot study for PC in 10 subjects with a series of 1-3...

Journal Article, Review

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tier0_review [What's new in aesthetic dermatology: filler and laser treatments]. Annales de dermatologie et de venereologie · 2009 · PMID 19576483

Abstract summary (English) In esthetic dermatology, filling and laser treatments are two essential techniques. Several recent studies on calcium hydroxyapatite in filling treatments and facial volumetry, in esthetics, but also in HIV patients, have been published. It was also tested in accentuated melomental folds where it is superior to hyaluronic acid.

English Abstract, Journal Article, Review

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tier0_review IPL technology: a review. Lasers in surgery and medicine · 2003 · PMID 12561039

Abstract summary (English) BACKGROUND AND OBJECTIVES: Intense pulsed light (IPL) systems are high-intensity light sources, which emit polychromatic light. Unlike laser systems, these flashlamps work with noncoherent light in a broad wavelength spectrum of 515-1,200 nm. These properties allow for great variability in selecting individual treatment parameters and adapting to different types of skin types and indications.

Journal Article, Review

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tier0_review Laser treatment of acquired vascular lesions. Dermatologic clinics · 1997 · PMID 9189676

Abstract summary (English) Several quasi-continuous wave and pulsed lasers can effectively treat a variety of vascular lesions. The PDL follows the theory of selective photothermolysis, is safe for infants and children, and has a low incidence of side effects. It is successful in treating telangiectasias, spider and cherry angiomas, pyogenic granulomas, venous lakes, and poikiloderma of Civatte, as well as small leg telangiectasias.

Journal Article, Review

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tier_other Vascular uses of LP1064 applicator on the harmony XL pro device. Journal of cosmetic dermatology · 2023 · PMID 37318789

Abstract summary (English) INTRODUCTION: Vascular lesions of the lower extremities and face, such as varicose veins and telangiectasias, are a common dilemma for the dermatologist. In recent years, laser therapy has emerged as a viable treatment option for these vascular anomalies. MATERIALS AND METHODS: Although there are several types of lasers, the 1064-nm Nd:YAG in particular is popularly selected for its safety profile and versatility.

Journal Article

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tier3 Fractional photothermolysis for treatment of poikiloderma of civatte. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2006 · PMID 16442059

Abstract summary (English) Poikiloderma of Civatte refers to a change in the skin where there is atrophy, hyper- and hypopigmentation, and dilation of fine blood vessels (telangiectasia). These alterations often cause cosmetic disfigurement, most commonly in middle-aged or elderly women with a fair complexion. Several treatment modalities, based on the theory of selective photothermolysis, including argon lasers, KTP lasers, pulsed dye...

Case Reports, Journal Article

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Suggested interpretation

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