Home · Pigment
Melasma (epidermal)
Compare the procedure groups used for this indication, ranked by evidence score. Grade reflects the volume and quality of research; direction reflects what the papers conclude.
| Grade | Score | Direction | Procedure group | RCT & meta | Clinical & observational | Case reports | Total papers |
|---|---|---|---|---|---|---|---|
| A | 69.5 | Supported | Picosecond laser pigment | 23 | 7 | 7 | 58 |
| A | 65.2 | Supported | Laser toning qswitched or picosecond | 39 | 20 | 13 | 125 |
| B | 60.8 | Supported | Fractional picosecond resurfacing | 7 | 2 | 0 | 24 |
| B | 59.0 | Supported | Chemical peel | 24 | 22 | 8 | 121 |
| B | 57.6 | Supported | Nonablative fractional resurfacing | 5 | 4 | 1 | 24 |
| B | 54.1 | Supported | Ionzyme iontophoresis sonophoresis | 6 | 4 | 2 | 15 |
| F | 0.0 | Insufficient | Needle free drug delivery | 0 | 0 | 0 | 0 |