Botulinum toxin a evidence for Mentalis chin dimpling

Abstract summary (English) BACKGROUND: Many popular botulinum neurotoxin treatments are off-label, yet no review has comprehensively captured their effects. This study provides a systematic review of neurotoxin's off-label aesthetic applications, focusing on muscle targets, aesthetic goals, outcomes, and patient satisfaction. METHODS: A systematic review of PubMed, MEDLINE, and Web of Science was conducted per Preferred Reporting Items for...

Journal Article, Systematic Review, Meta-Analysis, Research Support, Non-U.S. Gov't

Abstract summary (English) BACKGROUND: Botulinum toxin injection is the accepted standard treatment for synkinesis and gustatory hyperlacrimation in patients with facial paralysis. However, poor injection accuracy can result in inconsistent treatment outcomes, variable treatment durations, and complications. Ultrasound guidance should increase injection accuracy in the facial region; however, this has not been proven.

Randomized Controlled Trial, Journal Article, Research Support, Non-U.S. Gov't

Abstract summary (English) BACKGROUND: Nonsurgical correction of drooping of the corners of the mouth requires a multimodal approach combining botulinum toxin and soft tissue filler injections. OBJECTIVE: To validate a nonsurgical therapeutic approach for correcting a "saddened" appearance characterized by drooping mouth corners, oral commissures, and/or marionette lines. METHODS: In this prospective, evaluator-blinded study, monophasic...

Clinical Trial, Journal Article

Abstract summary (English) BACKGROUND: To address functional and smile dysfunction associated with post-facial paralysis synkinesis, the senior author (B.A.) has offered "modified selective neurectomy" of the lower division of the facial nerve as a long-term solution. This article examines technical considerations and outcomes of this procedure. METHODS: A retrospective review was conducted of patients who underwent modified selective...

Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't

Abstract summary (English) Botulinum toxin type A (BTX) injection into the orbicularis oculi muscle is an effective treatment for patients with hemifacial spasm (HFS). The objectives of this study were to investigate the effect of this treatment on HFS, in particular the associated hyperexcitability of the facial motor nucleus, and to discuss the potential mechanism of HFS. F waves in the mentalis muscle were examined before, 2 and 6 weeks...

Clinical Trial, Journal Article

Abstract summary (English) BACKGROUND: Botox has been used primarily for treating rhytids of the upper face. Its use in the lower part of the face has been reported by several authors but there is a relative scarcity of information regarding the use of Botox in the chin and even fewer well-controlled studies in this area. This study reports the findings from a placebo-controlled trial of Botox for the treatment of chin rhytids.

Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article

Abstract summary (English) BACKGROUND: The lower face conveys critical interpersonal signals and is central to how patients are emotionally evaluated by others. As botulinum toxin type A (BoNT-A) is increasingly used in the perioral and mandibular region, there is a growing need to understand how such procedures may influence both aesthetic outcomes and the dynamics of emotional communication and social perception. AIMS: This narrative review...

Journal Article, Review

Abstract summary (English) Neurotoxins are the most popular nonsurgical aesthetic procedure for men and women of all ages. Five botulinum toxin A (BoNTA) products represent the current palette of available BoNTA for cosmetic use. Off-label uses of BoNTA continue to expand and are now used for skin rejuvenation, to treat various skin disorders, and in facial nerve paralysis.

Journal Article, Review

Abstract summary (English) This study aimed to review the recent literature about botulinum toxin type A treatment patterns, including muscle targets, doses, duration of effect, adverse effects, and clinical outcomes in patients with postparetic synkinesis. A bibliographic research of studies published in the last 10 yrs was carried out on PubMed database, using the medical subject heading terms: botulinum toxin and synkinesis....

Journal Article, Review

Abstract summary (English) Botulinum toxin A was Food and Drug Administration approved in 2002 for the temporary correction of glabellar frown lines. Since that time, a variety of neuromodulators have established a convincing profile for both safety and efficacy in the treatment hyperdynamic rhytides of the upper face. With increasing clinical experience and expertise, these applications have been expanded to include targeted treatment of...

Journal Article, Review