Monopolar RF lifting evidence for Body skin laxity

Abstract summary (English) BACKGROUND: Radiofrequency microneedling (RFMN) is a prominent minimally invasive treatment for facial rejuvenation. While individual studies report positive outcomes, a comprehensive synthesis of evidence across efficacy, safety, and patient satisfaction is lacking. OBJECTIVES: To synthesize evidence on the aesthetic, safety, tolerability, and psychological outcomes of RFMN for facial rejuvenation.

Journal Article, Systematic Review, Review

Abstract summary (English) BACKGROUND: Needling radiofrequency (NRF) induces controlled dermal remodeling while preserving the epidermis. Rose stem cell-derived exosomes (RSCEs) possess regenerative and anti-inflammatory properties, but limited penetration restricts clinical utility. OBJECTIVES: To assess whether RSCEs applied immediately after NRF enhance improvement in wrinkles, texture, and pores in Asian patients.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: With the aging population, the demand for skin anti-aging treatments has been steadily rising, prompting the development of advanced non-invasive therapies. AIMS: To evaluate the efficacy and safety of microfocused ultrasound (MFU) combined with microneedle fractional radiofrequency (MFR) for facial rejuvenation. METHODS: This study involved 26 patients experiencing facial laxity.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Platelet-Derived Growth Factor BB (PDGF) is a potent stimulator of tissue regeneration. It has received FDA approvals in four medical therapeutic indications for tissue regeneration. Recently, the use of pure PDGF has also been introduced for the promotion of skin rejuvenation and regeneration in aesthetic indications.

Journal Article, Randomized Controlled Trial

Abstract summary (English) INTRODUCTION: Combining monopolar radiofrequency (RF) with targeted ultrasound (TUS), this study investigated whether these modalities promote facial rejuvenation through the production of hyaluronic acid (HA) in human skin. METHODS: Seven subjects (51-64 years, BMI 21.1-29.8 kg/m²) were enrolled and divided into three treatment groups in this single-center study; Group A (n = 3, simultaneous RF + TUS),...

Journal Article, Randomized Controlled Trial

Abstract summary (English) OBJECTIVES: To evaluate the efficacy and safety of a novel monopolar RF device for skin tightening and rejuvenation treatment. METHODS: Forty participants were enrolled in the study. Subjects randomized to the treatment group received a single treatment with the novel RF device (YOUMAGIC), whereas the control group received regular RF treatment (Thermage CPT; Solta Medical).

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Neck wrinkles are a prominent characteristic of skin aging, with recent studies indicating that interventions such as platelet-rich plasma (PRP), microneedling (MN), and radiofrequency (RF) can effectively rejuvenate aging skin. AIMS: This study aims to assess and compare the efficacy of three treatment modalities in addressing neck wrinkles. METHODS: Fifteen female participants with a neck Lemperle...

Journal Article, Randomized Controlled Trial, Comparative Study

Abstract summary (English) BACKGROUND: Radiofrequency (RF) microneedling produces patient discomfort which deters patients from completing the recommended treatment series. OBJECTIVE: The primary objective was to determine the tolerability, safety, and efficacy of a neurocosmetic postprocedure cream post-RF microneedling in reducing patient discomfort and enhancing recovery across the length of the study and, secondarily, to evaluate against...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: The microneedle fractional radiofrequency system (MFRS) is able to rejuvenate facial appearance by heating and coagulating certain depth of skin tissue. OBJECTIVE: To evaluate the safety and efficacy of a novel vacuum-assisted MFRS for facial contour tightening. METHODS: This prospective, randomized, split-face study included 21 patients who underwent three treatments with a vacuum-assisted MFRS at...

Journal Article, Randomized Controlled Trial

Abstract summary (English) Microneedle fractional radiofrequency (MFRF) has been used to improve photoaging and scars. This study aimed to evaluate the efficacy and safety of MFRF with basic fibroblast growth factor (bFGF) for facial atrophic acne scars and skin rejuvenation by blinded visual evaluation, self-report, and reflective confocal microscopy (RCM). Fifteen subjects were randomized to the MFRF with bFGF group and fifteen to the MFRF...

Journal Article, Randomized Controlled Trial