Vascular pigment laser 532 1064 evidence for Rosacea erythematotelangiectatic

Abstract summary (English) BACKGROUND: Pulsed dye laser (PDL) is widely used for erythematotelangiectatic rosacea (ETR); however, the influence of pulse duration remains unclear. OBJECTIVE: To compare the efficacy and tolerability of 6 and 10 ms PDL pulse durations for ETR. METHODS: In this single-center, prospective, randomized controlled study, 80 patients with ETR received single PDL treatment using either a 6 or 10 ms pulse duration (9-11...

Journal Article, Randomized Controlled Trial, Comparative Study

Abstract summary (English) UNLABELLED: Objective: Facial erythema and telangiectasia in rosacea are commonly treated with vascular lasers. Combination with ivermectin 1% cream, may enhance outcomes when combined with laser therapy. This study assesses whether topical ivermectin improves the efficacy of Potassium Titanyl Phosphate (KTP) 532 nm laser for facial erythema in rosacea.

Journal Article, Randomized Controlled Trial

Abstract summary (English) OBJECTIVES: To determine the effects of intense pulsed light (IPL) combined with meibomian gland expression (MGX) and topical medication on ocular rosacea and assess glutathione peroxidases (GPxs) change in the meibum after IPL treatments. METHODS: Ninety-six eyes of 48 participants with ocular rosacea were randomly assigned to either MGX with erythromycin eye ointment alone (control group) or the combination with...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND AND OBJECTIVES: Rosacea is a chronic inflammatory condition affecting the central face. While laser and energy-based devices (EBDs) are commonly used for managing vascular symptoms, comprehensive comparisons between systems are limited. This study aims to evaluate and compare the efficacy and safety of lasers and EBDs for rosacea through a systematic review and network meta-analysis (NMA).

Journal Article, Network Meta-Analysis, Systematic Review

Abstract summary (English) BACKGROUND: Current treatment options for facial erythema associated with acne and rosacea include oral and topical treatments. Physical modalities are also commonly used recently. Combination therapy usually works better than a single therapy.

Journal Article, Randomized Controlled Trial

Abstract summary (English) OBJECTIVE: The primary aim of this systematic review and meta-analysis was to synthesize and compare the clinical efficacy of intense pulsed light (IPL) and pulsed-dye laser (PDL) therapies for the management of rosacea. METHODS: The literatures were searched in the Web of Science, PubMed, Embase, and Cochrane Library databases to identify relevant studies investigating the use of IPL and PDL for the treatment of...

Comparative Study, Journal Article, Meta-Analysis, Systematic Review

Abstract summary (English) Background Rosacea is a chronic inflammatory disease of the skin characterised by facial erythema, oedema, telangiectasias, papules, pustules and nodules. There is a paucity of effective therapeutic modalities for the management of rosacea. Intense Pulsed Light (IPL), a modality in which flash lamps installed in an optical treatment device (head or tip) with mirrors to reflect light, has in recent times gained...

Journal Article, Systematic Review

Abstract summary (English) Previous clinical studies have shown that pulsed dye laser (PDL) and intense pulsed light (IPL) are effective for treating erythematotelangiectatic rosacea(ETR). This article aims to compare the efficacy and safety of PDL and IPL at three different wavelength bands (broad-band, single-narrow-band, and dual-narrow-band) in treating ETR. Sixty subjects with ETR were randomly categorized into four groups and received...

Journal Article, Randomized Controlled Trial, Comparative Study

Abstract summary (English) Rosacea is a common chronic skin disease distributed primarily around the central face. Ocular manifestations of rosacea are poorly studied, and estimates of prevalence vary widely, ranging from 6% to 72% in the rosacea population. Treatment options for ocular rosacea include lid hygiene, topical and oral antibiotics, cyclosporine ophthalmic emulsion, oral vitamin A derivatives, and intense pulsed light; however, a...

Systematic Review, Journal Article

Abstract summary (English) Rosacea changes are a result of an immune mediated response and the angiogenic properties of the LL-37 peptide. This peptide induces an inflammatory signal that activates the NLRP3-mediated inflammasome, triggering rosacea pathogenesis. Research findings show that LL-37 peptide is inhibited by binding to a cell surface glycosaminoglycan, heparan sulfate.

Randomized Controlled Trial, Journal Article