Vascular pigment laser 532 1064 evidence for Port wine stain

Abstract summary (English) BACKGROUND: Port-wine stain (PWS) is a disfiguring vascular anomaly characterized by persistent cutaneous erythema and progressive tissue hyperplasia. Although pulsed dye laser (PDL) is the first-line treatment and alleviates certain clinical manifestations, incomplete lesion clearance and high recurrence rates persist in some patients, posing significant therapeutic challenges. OBJECTIVE: To evaluate the efficacy...

Journal Article, Randomized Controlled Trial

Abstract summary (English) OBJECTIVE: This study aims to comprehensively review and compare the safety and efficacy of commonly used lasers in the management of head and neck capillary malformations (CMs). DATA SOURCES: PubMed, Embase, Cochrane, and Web of Science. REVIEW METHODS: Databases were searched from inception to August 2023.

Journal Article, Systematic Review, Meta-Analysis

Abstract summary (English) BACKGROUND: Despite numerous studies over the past two decades, clinical treatment for port wine stains (PWS) has shown limited progress. Analyzing evolutionary trends and research focal points can illuminate current deficiencies and guide future investigations. We aim to conduct a scientometric analysis and meta-analysis to uncover the historical trajectory, research hotspots, and future directions of PWS.

Journal Article, Meta-Analysis

Abstract summary (English) Port-wine birthmarks (PWB) are common vascular malformations in infants. Despite various laser and light-based treatments, comparative data on their effectiveness is limited. This study compares different treatments for PWB using a systematic review and network meta-analysis (NMA).

Journal Article, Systematic Review, Network Meta-Analysis

Abstract summary (English) INTRODUCTION: The 595-nm wavelength pulsed dye laser (PDL) is well-established in the treatment of vascular lesions. In June 2023, it received FDA clearance for the treatment of port-wine birthmarks (PWB) and infantile hemangiomas (IH) in the pediatric population. OBJECTIVE: Review the evidence regarding the efficacy, safety, and implications of using PDL for management of pediatric PWB and IH.

Journal Article, Systematic Review

Abstract summary (English) BACKGROUND: Pulsed dye lasers (PDL) are currently the first-line treatment of port-wine birthmarks (PWB). Due to high maintenance costs and instable technology, alternative methods are needed. OBJECTIVES: To compare clinical outcomes of a variable-sequenced, long-pulsed 532-nm potassium titanyl-phosphate (KTP) laser and PDL on treating PWB.

Journal Article, Randomized Controlled Trial, Comparative Study

Abstract summary (English) OBJECTIVES: The current gold standard treatment for port-wine stains (PWS) is pulsed dye laser (PDL). However, multiple treatment sessions may be necessary and complete resolution is often not achieved. Neoangiogenesis can occur soon after treatment and is thought to be a major factor contributing to treatment failure.

Systematic Review, Case Reports, Research Support, Non-U.S. Gov't, Journal Article

Abstract summary (English) Pulsed dye laser (PDL) is the most commonly used method for port-wine stain (PWS); however, no studies have reported the safety of PDL. This review aimed to collect and summarize complications reported in relevant literature, assess complication rates in treating PWS with PDL, and explore the relevant influencing factors. A systematic review and meta-analysis were conducted to search for related studies in PubMed,...

Meta-Analysis, Systematic Review, Journal Article

Abstract summary (English) The pulsed dye laser (PDL) is the standard treatment for port-wine stains (PWS). Maximal improvement occurs after multiple treatment sessions; however, the optimal treatment interval has yet to be determined. The aim of this study was to review whether there is an association between PDL treatment interval and outcome of PWS.

Journal Article, Meta-Analysis, Systematic Review

Abstract summary (English) BACKGROUND: Pulsed dye laser (PDL) treatment currently represents the mainstream choice for port-wine stain (PWS) treatment in accordance with selective photothermolysis. However, most PWS lesions cannot be removed despite several treatments. Intense pulsed light (IPL) is reportedly an effective alternative to PDL for PWS treatment.

Comparative Study, Journal Article, Randomized Controlled Trial