Skin Quality · Photodamaged skin / texture
Placenta injection evidence for Photodamaged skin / texture
There is not yet enough PubMed evidence for this combination. The procedure exists, but research on this indication may be scarce.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Median year 2022 Last 5 years 50% Positive results 25% Korea/Asia 1
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier1 Efficacy of porcine placental extract on wrinkle widths below the eye in climacteric women.
Abstract summary (English) OBJECTIVE: Injections of human placental extract, which is known to play a role in skin regulation, have long been used for the treatment of skin wrinkles and non-healing wounds. Porcine placental extract (PPE), an oral supplement, was recently developed for this purpose. The aim of this study was to assess whether PPE has a positive effect on the improvement of fine wrinkles below the eye in climacteric women.
Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't
View on PubMedtier_other Antioxidant Capacity and Protective Effect of Cow Placenta Extract on D-Galactose-Induced Skin Aging in Mice.
Abstract summary (English) Placental extract has been used for skin care and delaying skin aging. Cow placenta is an abundant resource with a large mass, which has not been harnessed effectively. Cow placenta extract (CPE) has the functions of antioxidation, anti-inflammatory, promoting growth and development, and promoting hair growth.
Journal Article
View on PubMedtier_other Human placental extract activates a wide array of gene expressions related to skin functions.
Abstract summary (English) As skin aging is one of the most common dermatological concerns in recent years, scientific research has promoted treatment strategies aimed at preventing or reversing skin aging. Breakdown of the extracellular matrix (ECM), such as collagen and elastin fibers, in the skin results in decreased skin elasticity and tension. Cutaneous cells, especially fibroblasts in the dermis layer of the skin, mainly produce ECM...
Journal Article
View on PubMedtier_other Evaluation of fibroblast growth factor activity exerted by placental extract used as a cosmetic ingredient.
Abstract summary (English) BACKGROUND: The biological activities claimed for placental extract (PE) in its medical and cosmetic applications are largely assumed to be the combined effects of its various signaling molecules and nutritional constituents. But there are considerable uncertainties about this assumption. AIMS: To determine the specific biological activity of PE at a molecular level.
Journal Article
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