Placenta injection evidence for Chronic wound / diabetic ulcer

Abstract summary (English) BACKGROUND: Human placental hydrolysate (hPH) contains anti-inflammatory substances. This study aimed to analyze whether injecting hPH into the subacromial space could reduce pain in patients with shoulder impingement syndrome. METHODS: This single-blind, randomized controlled study enrolled 50 patients with shoulder impingement syndrome who were randomly assigned to either the hPH or placebo groups.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Chronic radiation cystitis occurs a minimum of three months after completion of pelvic radiotherapy and represents a range of clinical symptoms for which there is as yet no recommended standard management. OBJECTIVES: The aim of this review was to identify the various non-surgical treatment options for the management of late chronic radiation cystitis and evaluate the evidence. SEARCH STRATEGY: Synonyms...

Journal Article, Systematic Review

Abstract summary (English) To evaluate human placental extract in the treatment of radiation mucositis involving the oral/oropharyngeal region, a prospective randomized study was carried out in 120 patients with squamous cell carcinoma of the head and neck from August 1997 to March 1999. The study was conducted in patients receiving radical external radiation therapy, planned for = > 60 Gy/30 F/6 weeks, who developed grade 2 radiation...

Clinical Trial, Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Despite the availability of a wide range of agents, no single treatment exists for the management of radiation-induced oral mucositis, in patients, with head and neck malignancies, on radical chemoradiation; a debilitating and limiting sequela. Human placental extract is one option that has been proposed. AIMS AND OBJECTIVES: This study aimed at evaluating the therapeutic benefits of human placental...

Journal Article, Comparative Study

Abstract summary (English) Topical wound-healing potential of autologous bone marrow-derived nucleated cells along with placental extract was evaluated in comparison with buffy coat of autologous blood on full-thickness cutaneous wounds in the thoracolumbar region of 15 clinically healthy New Zealand rabbits. Three wounds of 2 × 2 cm, one on the right side of the body and two on the left side of the midline were created on the dorsal lumbar...

Comparative Study, Journal Article

Abstract summary (English) Iontophoretic application of Placenta-Lucchini in combination with catalase and mucopolysaccharidase for the treatment of acute rheumatic inflammation results in significant clinical improvement. Such improvement is not seen if Placenta is used alone. Intra-articular application of Placenta in the arthritis joints of patients with rheumatoid arthritis results in a significant improvement as compared with placebo.

Clinical Trial, Controlled Clinical Trial, Journal Article

Abstract summary (English) BACKGROUND: Environmental changes affecting pet animals, along with an increase in age-related conditions and diseases among pets, have become increasingly evident. Despite this trend, there remains a paucity of research on therapeutic approaches for geriatric companion animals. CASE DESCRIPTION: The case report describes a 19-year-old spayed female cat that was diagnosed with chronic renal failure and recurrent...

Case Reports, Journal Article

Abstract summary (English) BACKGROUND: Canine corneal disease is a common condition encountered in daily practice. If the depth of corneal damage is limited to the epithelial layer, healing is often straightforward; however, if it extends into the epithelial basement membrane or corneal parenchyma, surgical treatment is the treatment of choice. Moreover, in cases where there is an underlying disease or where the owner refuses surgical...

Case Reports, Journal Article

Abstract summary (English) Acute radiation cystitis occurs during or soon after radiation treatment. It is usually self-limiting, and is generally managed conservatively. Late radiation cystitis, on the other hand, can develop from 6 months to 20 years after radiation therapy.

Journal Article, Review

Abstract summary (English) Local injections of corticosteroids or human placental extracts are sometimes used for the treatment of resistant tendinitis or fasciitis. We report a case of infectious Achilles tendinitis complicated by calcaneal osteomyelitis after injection of human placental extracts for the Achilles tendinitis. She was treated with excision of the infected bone and tendon, followed by V-Y lengthening of the proximal portion of...

Case Reports, Journal Article