GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Lifting / Laxity · Lower face / jowls

Pdo PCL PLLA thread lifting evidence for Lower face / jowls

C 35.6 / 100 Supported 0 RCT/meta · 0 clinical/observational · 5 case · 13 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2021 Last 5 years 54% Positive results 54% Negative results 1 Korea/Asia 1

Known in Korea as

돌기실모노실민트실압토스잼버실LSCO아이쓰레드맞춤 실리프팅실루엣 Fit실루엣 소프트

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier3 A case of hypertension due to iatrogenic glossopharyngeal neuropathy after aesthetic procedure. Acta neurochirurgica · 2025 · PMID 41032126

Abstract summary (English) In our case, we report a previously unreported complication of a thread lift procedure in the jowl region. This complication was caused by damage to the glossopharyngeal nerve through compression. The case also illustrates the diagnostic and therapeutic aspects of iatrogenic injury to the glossopharyngeal nerve.

Journal Article, Case Reports

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tier3 Chronic Facial Paralysis Treated With Non-absorbable APTOS Barbed Threads: A Case Report With Anatomic Considerations. Cureus · 2024 · PMID 39022483

Abstract summary (English) Chronic paralysis of the facial nerve leads to degenerative facial muscle and surrounding soft tissue alterations on the involved side, making the affected patients seem older than their actual age. Moreover, contralateral facial hypertrophy worsens facial asymmetry. Correction of the drooping or wrinkled face due to aging, trauma, or other pathology has been successfully treated with the thread-lifting technique.

Case Reports, Journal Article

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tier3 Iatrogenic Glossopharyngeal Neuropathy in Aesthetic Practice: A Case Report. Plastic and reconstructive surgery. Global open · 2022 · PMID 35291331

Abstract summary (English) Iatrogenic glossopharyngeal nerve injuries are commonly associated with procedures such as a tonsillectomy, carotid endarterectomy, and endotracheal intubation. We present a previously unreported complication of a thread lift procedure in the jowl region, causing damage to the glossopharyngeal nerve through compression. The glossopharyngeal nerve belongs to the bulbar group of the cranial nerves.

Case Reports, Journal Article

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tier3 An innovative thread-lift technique for facial rejuvenation and complication management: A case report. Medicine · 2018 · PMID 29794731

Abstract summary (English) RATIONALE: Aging of face is an unavoidable process. Traditional procedures for facial rejuvenation have multiple disadvantages. In this case report, we used an innovative technique combining thread lift with small incision rhytidectomy for facial rejuvenation.

Case Reports, Journal Article

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tier3 Lifting the Lower Face With an Absorbable Polydioxanone (PDO) Thread. Journal of drugs in dermatology : JDD · 2017 · PMID 28915290

Abstract summary (English) Traditional rejuvenation techniques include chemical peels, rhytidectomy of the skin, laser resurfacing, injection of dermal fillers and neurotoxins, and invasive surgical procedures. Patients with brow ptosis, jowl formation, and deepening nasolabial folds currently seek antiaging procedures with no incisions and minimal downtime such as thread-lifting with barbed sutures. The present report describes a case in...

Case Reports, Journal Article

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tier_other Retrograde approach to mid-face thread lift with reverse temporal vectors: an innovative insight into the conventional approach. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2026 · PMID 41902759

Abstract summary (English) The retrograde approach to mid-face thread lift, utilizing reverse temporal vectors, offers an innovative advancement in minimally invasive facial rejuvenation. This study evaluates its efficacy and safety in 20 female patients aged 30-60 years presenting with moderate midface ptosis but minimal jowling and neck laxity. The technique involves inserting poly L-lactide-co-ε-caprolactone bi-directional threads into...

Journal Article

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tier_other Polydioxanone (PDO) Thread Lift for Face: A Novel Anatomical Approach. Plastic and reconstructive surgery · 2026 · PMID 41534851

Abstract summary (English) Barbed thread facelift has grown in popularity, however, optimal strategies for thread placement remain inconclusive. Currently, most practitioners use cannula-driven method for thread facelifts. However, the lifts are generally performed without firm anchors, and many cephalad barbs remain unused.

Journal Article

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tier_other A Retrospective Observational Study of Combination Treatment of Thread Lift and High-intensity Focused Ultrasound for Facial Aging. Plastic and reconstructive surgery. Global open · 2025 · PMID 40520495

Abstract summary (English) BACKGROUND: Current literature lacks guidelines on the optimal treatment number of threads for specific indications and provides limited evidence on the efficacy of combining thread lift with other materials or devices for synergistic effects. METHODS: This study evaluates the therapeutic outcomes of combining thread lift therapy with high-intensity focused ultrasound. Fifty-eight participants, divided into 2 groups...

Journal Article

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tier_other Thread Lifting of the Jawline: A Pilot Study for Quantitative Evaluation. Journal of cutaneous and aesthetic surgery · 2021 · PMID 34084008

Abstract summary (English) INTRODUCTION: The facial aging process produces changes that are characteristic of the superficial and deep fat framework and skin layers. Subdermal suspension with threads enables the sagging tissues to be lifted by means of a minimally invasive, closed procedure without surgical dissection. This observational study has been carried out on the basis of standardized tridimensional photographic analysis and...

Journal Article

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tier_other Vertical Lifting: A New Optimal Thread Lifting Technique for Asians. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2017 · PMID 28430736

Abstract summary (English) BACKGROUND: With the evolution of facial rejuvenation methods, thread lifts have gained popularity among patients who seek cosmetic improvement. Absorbable wedge-shaped polydioxanone (PDO) sutures are currently available, and they are extremely popular in the aesthetic clinics in Korea. In case of midface and mandibular jowl lift, threads are most often inserted in an oblique manner with vectors of rejuvenation...

Journal Article

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Suggested interpretation

Minimal evidence

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