Skin Quality · Photodamaged skin / texture
Nonablative fractional resurfacing evidence for Photodamaged skin / texture
There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Median year 2019 Last 5 years 42% Positive results 69% Negative results 4 Korea/Asia 15
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier1 Efficacy of combined 1927 nm thulium fiber laser and supramolecular salicylic acid in photoaging treatment.
Abstract summary (English) PURPOSE: 1927 nm fractional thulium fiber laser (TFL) has been shown to be effective in improving skin appearance by reducing pigmentation and loss of elasticity caused by photoaging. Supramolecular salicylic acid (SSA) has been utilized for chemical peeling with rejuvenation effect. This study aims to evaluate the effectiveness and safety of combined TFL and SSA treatment for photoaging.
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Prospective, Split-Face Randomized Clinical Trial Comparing Non-ablative Fractional Laser for Periorbital Photoaging in Different Age Groups.
Abstract summary (English) BACKGROUND: The 1550 nm and 1565 nm non-ablative fractional lasers (NAFL) have recently been introduced as treatments for periorbital photoaging. This prospective, randomized split-face trial aimed to evaluate the safety and effectiveness of these NAFL treatments in addressing periorbital photoaging in Asian patients across various age groups. METHODS: Eighteen patients completed the study, with nine under 45 (Group...
Journal Article, Randomized Controlled Trial, Comparative Study
View on PubMedtier1 Comparative analysis of erbium: glass 1550 nm and combined erbium: YAG & Nd: YAG lasers for perioral rejuvenation: a prospective study.
Abstract summary (English) Perioral aging manifests as fine lines, wrinkles, and structural changes, often requiring specialized treatment. Although laser systems are widely used in facial rejuvenation, few studies directly compare their efficacy in perioral rejuvenation. This study evaluates and compares the efficacy and safety of two laser systems-Erbium: glass laser and Nd: YAG combined with Er: YAG laser-for perioral rejuvenation.
Journal Article, Comparative Study, Randomized Controlled Trial
View on PubMedtier1 Nonablative Fractional 1927-nm Laser for Periorbital Rejuvenation: A Prospective, Double-Arm, Open-Label Trial.
Abstract summary (English) BACKGROUND: The 1927-nm nonablative fractional laser is widely used for skin rejuvenation and hyperpigmentation. However, its efficacy and safety for periorbital rejuvenation remain uncertain. AIMS: To assess the effects of the 1927-nm nonablative fractional diode laser on periorbital rejuvenation.
Journal Article, Randomized Controlled Trial
View on PubMedtier1 A Randomized, Investigator-Blinded, Split-Face, Controlled Trial Assessing Efficacy and Satisfaction of CE Ferulic Serum Following Nonablative Fractional Fraxel Laser Treatment for Photoaging Skin in Chinese Population.
Abstract summary (English) BACKGROUND: Following Nonablative fractional Fraxel laser (NAFL), a well-established treatment for skin rejuvenation, immediate post-procedural care is essential to address any potential complications and accelerate the healing process. AIMS: To evaluate the efficacy and patient satisfaction of a topical skincare regimen containing vitamin C, vitamin E, and ferulic acid-CE Ferulic serum (CEF) following NAFL...
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Comparison of Intense Pulsed Light With Nonablative Fractional Laser and Picosecond Alexandrite Laser With Diffractive Lens Array for Noninvasive Facial Rejuvenation.
Abstract summary (English) BACKGROUND: Both nonablative fractional (NAFL) laser combined with intense pulsed light (IPL) and picosecond alexandrite laser (PSAL) with diffractive lens array (DLA) have been documented for their efficacy in facial rejuvenation. OBJECTIVE: To observe the safety and efficacy of PSAL-DLA and IPL-NAFL in the rejuvenation of Chinese individuals. METHODS: Each subject (n = 18) received three treatments on half of...
Journal Article, Comparative Study, Randomized Controlled Trial
View on PubMedtier1 A Multi-Component Reaction Peptide Augmenting the Anti-Aging Benefits of Non-Ablative Laser Procedure.
Abstract summary (English) BACKGROUND: Laser resurfacing is one of the most popular aesthetic procedures that address a wide range of skin conditions and overall skin rejuvenation. To reduce downtime and improve the clinical efficacy of the procedures, it is important to design post-procedure care routines to complement them. Towards fulfilling that consumer need, a peptide synthesized from multi-component reaction (MCP) has been developed.
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Randomized split-face study using a post-procedural biotech cellulose mask to improve patient comfort and downtime.
Abstract summary (English) BACKGROUND: There are many post-procedural treatments touted to improve comfort and decrease downtime, but very few prospective randomized studies. AIMS: To analyze the safety and efficacy of a post-procedural biotech cellulose mask. PATIENTS/METHOD: Fifteen patients undergoing either a microneedling with radiofrequency (n = 5), non-ablative fractional (n = 5), or full erbium:YAG resurfacing (n = 5) treatment were...
Randomized Controlled Trial, Journal Article
View on PubMedtier1 Efficacy and Safety of Intense Pulsed Light and Nonablative Fractional 1440-nm Diode Laser to a Combination of the 2 Modalities for Facial Rejuvenation.
Abstract summary (English) BACKGROUND: The aging process involves laxity, hyperpigmentation, and telangiectasias. It is important to target those elements of aging to be successful at achieving rejuvenation. OBJECTIVE: To determine the efficacy, safety, and patient satisfaction of a combination intense pulsed light (IPL) and 1440-nm diode laser versus either treatment alone.
Randomized Controlled Trial, Journal Article
View on PubMedtier1 The Efficacy and Safety of Radiofrequency Microneedling Versus a Nonablative Fractional 1,550-nm Erbium:Glass Laser for the Rejuvenation of the Neck.
Abstract summary (English) BACKGROUND: Radiofrequency microneedling (RFMN) and nonablative fractional 1,550-nm erbium:glass lasers (NAFLs) have been reported to be used with success in neck rejuvenation. There are no head-to-head trials to compare these modalities. OBJECTIVE: The purpose of the study was to compare the efficacy and safety of radiofrequency microneedling and nonablative fractional 1,550-nm erbium:glass lasers for the...
Journal Article, Randomized Controlled Trial
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