GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Acne / Scar / Texture · Atrophic acne scar - rolling

Nonablative fractional resurfacing evidence for Atrophic acne scar - rolling

B 53.2 / 100 Supported 2 RCT/meta · 1 clinical/observational · 0 case · 6 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2023 Last 5 years 50% Positive results 67% Negative results 1 Korea/Asia 1

Known in Korea as

라셈드MOXI헤일로 레이저

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Efficacy and Safety of Er:Glass versus CO2 Lasers in the Treatment of Atrophic Acne Scars: A Systematic Review and Meta-Analysis. Aesthetic plastic surgery · 2025 · PMID 41364211

Abstract summary (English) BACKGROUND: Fractional laser therapy is a cornerstone for atrophic acne scar treatment. While both ablative fractional CO2 and non-ablative fractional Er:Glass lasers are widely used, comprehensive comparative data on their efficacy, patient satisfaction, and complication profiles remain limited. This meta-analysis aimed to quantitatively compare these outcomes.

Journal Article, Systematic Review, Meta-Analysis, Comparative Study, Review

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tier1 Comparison of multiple 1565 nm fractional Er: glass laser and single fractional CO2 laser in the treatment of atrophic acne scars: a prospective, randomized split-face study. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2025 · PMID 39930716

Abstract summary (English) Both ablative fractional laser (AFL) and non-ablative fractional laser (NAFL) are gaining popularity in the treatment of atrophic acne scars. However, single NAFL may not be as effective as single AFL in clinical practice. This split-face and evaluator-blind study compared the efficacy and safety of multiple consecutive NAFL (1565 nm Er: glass laser) and a single AFL (10600 nm CO2 laser) in the treatment...

Journal Article, Randomized Controlled Trial, Comparative Study

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tier2 Efficacy and safety of 1550-nm fractional laser in the treatment of acne scars in Chinese patients: A split-face comparative study. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2016 · PMID 27183153

Abstract summary (English) OBJECTIVE: To evaluate the efficacy and side effects of 1550-nm fractional Er:Glass laser in treating atrophic acne scar. MATERIALS AND METHODS: Thirty Chinese patients aged 18-65 with atrophic acne scars on both cheeks received a split-face treatment, one side with four sessions of treatment with fractional 1550-nm Er:Glass laser at 20-day interval and the other with topical asiaticoside cream application three...

Comparative Study, Journal Article

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tier0_review Laser treatment for facial acne scars: A review. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2018 · PMID 30395754

Abstract summary (English) BACKGROUND AND OBJECTIVES: Acne scarring is a widely prevalent condition that can have a negative impact on a patient's quality of life and is often worsened by aging. A number of options are available for the treatment of acne scarring, including retinoids, microdermabrasion, dermal fillers, and surgical techniques such as subcision. The aim of this review is to evaluate the different laser modalities that have...

Journal Article, Review

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tier_other Clinical Factors Affecting the Effectiveness of 1550-nm Erbium-Doped Fractional Photothermolysis Laser for Individual Atrophic Acne Scar Types. Dermatology and therapy · 2023 · PMID 36631628

Abstract summary (English) INTRODUCTION: Although non-ablative fractional resurfacing is frequently used for atrophic acne scars, few studies have examined clinical factors affecting the effectiveness of non-ablative fractional laser in individual atrophic acne scar types (icepick, rolling, and boxcar scars). Herein, we evaluated the clinical factors affecting the effect of non-ablative fractional laser for individual atrophic acne scar types...

Journal Article

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tier_other Which type of atrophic acne scar (ice-pick, boxcar, or rolling) responds to nonablative fractional laser therapy? Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2014 · PMID 24447255

Abstract summary (English) BACKGROUND: Few studies have examined the role of fractional lasers in individual acne scars (ice-pick, box car, rolling) using objective assessment tools in darkly pigmented skin. OBJECTIVE: To evaluate the effect of 1,540-nm fractional lasers on individual acne scars. METHODS AND MATERIALS: A prospective interventional study was conducted in 35 patients using a 1,540-nm fractional laser.

Journal Article

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Suggested interpretation

Limited evidence

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