GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Body / Fat · Thigh fat

Monopolar RF lifting evidence for Thigh fat

C 41.9 / 100 Supported 9 RCT/meta · 44 clinical/observational · 18 case · 153 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2012 Last 5 years 10% Positive results 49% Negative results 8 Korea/Asia 1

Known in Korea as

덴서티볼뉴머세르프써마지올리지오올타이트울써마지튠라이너튠페이스올리지오X

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Recovery and patient satisfaction following radiofrequency ablation and concomitant foam sclerotherapy of varicose veins with and without compression: A randomized controlled non-inferiority trial. Phlebology · 2022 · PMID 35232310

Abstract summary (English) BACKGROUND: The benefits of postoperative compression are not well established following radiofrequency ablation of the truncal vein and concomitant foam sclerotherapy. METHODS: A total of 104 patients were randomized: Postoperatively, 54 patients received no compression and 50 patients received class II thigh-high compression. The primary outcome for this study was the difference between means on postoperative pain...

Journal Article, Randomized Controlled Trial, Equivalence Trial

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tier1 Skin thermophysiological effects of 448 kHz capacitive resistive monopolar radiofrequency in healthy adults: A randomised crossover study and comparison with pulsed shortwave therapy. Electromagnetic biology and medicine · 2018 · PMID 29308927

Abstract summary (English) Radiofrequency-based electrophysical agents (EPA) have been used in therapy practice over several decades (e.g., shortwave therapies). Currently, there is insufficient evidence supporting such devices operating below shortwave frequencies. This laboratory-based study investigated the skin physiological effects of 448 kHz capacitive resistive monopolar radiofrequency (CRMRF) and compared them to pulsed shortwave...

Comparative Study, Journal Article, Randomized Controlled Trial

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tier1 Thermal build-up, decay and retention responses to local therapeutic application of 448 kHz capacitive resistive monopolar radiofrequency: A prospective randomised crossover study in healthy adults. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2015 · PMID 26524223

Abstract summary (English) PURPOSE: Radiofrequency-based electrophysical agents are widely used in therapy-related clinical practice for their thermal effects, mainly relieving pain and inflammation and improving tissue extensibility. The most commonly used and researched are shortwave therapies that operate at 27.12 MHz. Although relatively new, electrophysical agents employing much lower frequencies have also emerged.

Journal Article, Randomized Controlled Trial

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tier1 Efficacy and survival analysis of percutaneous radiofrequency versus microwave ablation for hepatocellular carcinoma: an Egyptian multidisciplinary clinic experience. Surgical endoscopy · 2014 · PMID 24935203

Abstract summary (English) BACKGROUND: Hepatocellular carcinoma (HCC) is a primary tumor of the liver with poor prognosis. For early stage HCC, treatment options include surgical resection, liver transplantation, and percutaneous ablation. Percutaneous ablative techniques (radiofrequency and microwave techniques) emerged as best therapeutic options for nonsurgical patients.

Journal Article, Randomized Controlled Trial

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tier1 Complementary clinical effects of topical tightening treatment in conjunction with a radiofrequency procedure. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2014 · PMID 24927068

Abstract summary (English) UNLABELLED: Abstract Background: Skin laxity and cellulite on the buttocks and thighs are two common cosmetic concerns. Skin tightening with radiofrequency (RF) devices has become increasingly popular. OBJECTIVE: The purpose of this study is to evaluate the efficacy and safety of a topical skin laxity tightening agent when used in combination with an RF device.

Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier1 Effects of whole-body vibration with or without localized radiofrequency on anthropometry, body composition, and motor performance in young nonobese women. Journal of alternative and complementary medicine (New York, N.Y.) · 2012 · PMID 22268971

Abstract summary (English) OBJECTIVES: The study investigated the effect of whole-body vibration (WBV) alone and in association with localized radiofrequency on fat deposits in young nonobese subjects. METHODS: Forty-four (44) healthy, nonobese women aged 25.3±5.26 years, body-mass index (BMI) 21.7±2.47 kg/m(2) were randomly assigned to an 8-week trial of WBV (2 sessions per week) or WBV plus localized radiofrequency (WBV+RF) in the...

Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier1 Unipolar radiofrequency treatment to improve the appearance of cellulite. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2008 · PMID 18788033

Abstract summary (English) BACKGROUND: Previous studies suggest that radiofrequency (RF) energy may be effective as a treatment for cellulite. OBJECTIVE: This bilateral paired blinded comparative study assesses the efficacy and safety of a unipolar RF device for improving the appearance of cellulite using a new quantitative cellulite grading system. METHODS: In this randomized, blinded, split-design study, 10 individuals (aged 32-57 years)...

Journal Article, Randomized Controlled Trial

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tier1 A single center, randomized, comparative, prospective clinical study to determine the efficacy of the VelaSmooth system versus the Triactive system for the treatment of cellulite. Lasers in surgery and medicine · 2006 · PMID 17163477

Abstract summary (English) BACKGROUND AND OBJECTIVES: One area of cosmetic concern for women of all races is the unsightly appearance of cellulite in the buttocks area and lower extremities. Two modern technological advances claim to improve cellulite and provide reproducible results, TriActive and VelaSmooth. The TriActive laser is intended to reduce the appearance of cellulite through the combination of low-energy diode laser, contact...

Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier1 Radiofrequency endovenous obliteration versus stripping of the long saphenous vein in the management of primary varicose veins: 3-year outcome of a randomized study. Annals of vascular surgery · 2005 · PMID 16052388

Abstract summary (English) We evaluated the 3-year outcome of a series of patients with primary varicose veins who were randomized to radiofrequency endovenous obliteration vs. stripping of the long saphenous vein (LSV). Twenty-eight patients were included in the study: 15 were randomized to the radiofrequency endovenous obliteration procedure and 13 to LSV stripping.

Journal Article, Randomized Controlled Trial

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tier2 Effectiveness of Body Remodeling and Cellulite Appearance Improvement Treatments in the Thighs Using Symmed Radiofrequency Device. Journal of cosmetic dermatology · 2025 · PMID 39815666

Abstract summary (English) BACKGROUND: Aging associated with the passage of time causes alterations in subcutaneous tissues and the overall appearance of the skin that generate aesthetic unconformities in people. Within the wide range of available techniques on the market, radiofrequency (RF) diathermy has emerged as one of the most used non-invasive methods to combat them. OBJECTIVE: This clinical trial aims to determine and quantify the...

Journal Article, Clinical Trial

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