GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Lifting / Laxity · Body skin laxity

Microwave 245ghz skin tightening evidence for Body skin laxity

B 51.9 / 100 Supported 1 RCT/meta · 3 clinical/observational · 1 case · 9 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2023 Last 5 years 78% Positive results 89% Korea/Asia 1

Known in Korea as

온다ONDA 리프팅

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Microwaves Versus Combined Microwaves and Fractional Carbon Dioxide Laser in the Treatment of Postpartum Abdominal Laxity Among Filipino Patients in a Tertiary Hospital: A Randomized, Prospective, Assessor-Blinded, Simultaneous Split-Abdomen Trial. Journal of cosmetic dermatology · 2025 · PMID 40371814

Abstract summary (English) BACKGROUND: Postpartum abdominal laxity is a growing concern for women. Noninvasive options like microwave technology and fractional carbon dioxide (CO2) laser show promise, but their combined efficacy and safety require further investigation. AIM: To compare the efficacy and safety of microwaves versus combined microwaves and fractional CO2 laser in the treatment of postpartum abdominal laxity...

Journal Article, Randomized Controlled Trial, Comparative Study

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tier2 Efficacy and Safety of Microwave Energy-Based Device for Facial Rejuvenation: A Retrospective Comparative Study With High-Intensity Focused Ultrasound. Aesthetic surgery journal · 2026 · PMID 41403025

Abstract summary (English) BACKGROUND: Facial aging is characterized by soft tissue atrophy, subcutaneous fat redistribution, and dermal laxity, most pronounced in the lower face and submental region. High-intensity focused ultrasound (HIFU) is the benchmark noninvasive lifting modality, whereas microwave energy-based devices (MEBDs) have recently emerged, targeting adipose tissue and dermis. Although MEBD has been validated in body...

Journal Article, Comparative Study

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tier2 Three-dimensional analysis for measuring volumetric changes after a noninvasive treatment performed with a new system delivering microwave energy for unwanted abdominal fat reduction. Journal of cosmetic dermatology · 2023 · PMID 37313632

Abstract summary (English) BACKGROUND: A growing demand for aesthetic treatments for localized abdominal unwanted fat has developed as a healthy lifestyle is not always able to improve abdomen appearance. AIMS: The purpose of this retrospective nonrandomized observational study was to evaluate the efficacy and safety of a new device delivering microwaves energy for unwanted fat reduction, using three-dimensional (3D) imaging analysis....

Observational Study, Journal Article

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tier2 Use of a microwave device for the treatment of cellulite and localized fat adiposity: a 1-year follow-up study. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023 · PMID 37522509

Abstract summary (English) BACKGROUND: The body contour market has grown steadily over the last years, due to the persistent demand for non-invasive treatments for localized fat adiposities, cellulite, and skin laxity. MATERIALS AND METHODS: The purpose of this observational study was to evaluate the efficacy and safety of a new device delivering microwaves (MWs) energy for unwanted fat and cellulite reduction after a full cycle of treatments...

Observational Study, Journal Article, Retracted Publication

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tier3 Microwave Therapy for Frostbite Management: A Case Series. Journal of medical cases · 2023 · PMID 37435105

Abstract summary (English) Microwave body tightening and contouring is a common and efficient cosmetic medical procedure. The current study presents preliminary data about microwave treatment for body contouring where an innovative and unexpected benefit on frostbites was shown. This is a case series on two patients with frostbite treated with microwave therapy.

Case Reports, Journal Article

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tier_other An innovative microwave technology for the treatment of submental skin laxity. Lasers in medical science · 2025 · PMID 39841282

Abstract summary (English) BACKGROUNDS AND AIMS: Submental skin laxity (SSL), manifesting as sagging skin and double chin, can significantly affect patients' self-perception and social interactions. While surgical treatments exist, non-invasive methods are increasingly sought for their minimal recovery time. This study assesses the safety and effectiveness of a novel microwave-based device for treating SSL, aiming to provide long-term...

Journal Article

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tier_other Non-invasive system delivering microwaves energy for unwanted fat reduction and submental skin tightening: Clinical evidence. Journal of cosmetic dermatology · 2022 · PMID 35778895

Abstract summary (English) BACKGROUND: Cervicomental contour represents an important aesthetic problem. AIMS: This research evaluates the safety and the efficacy of a new non-invasive system delivering microwave energy for the treatment of submental skin laxity and fat. METHODS: Forty-eight subjects underwent submental treatment with the device at hand at Poliambulatorio San Michele, Reggio Emilia, Italy.

Journal Article

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tier_other Combined microwaves and fractional microablative CO2 laser treatment for postpartum abdominal laxity. Journal of cosmetic dermatology · 2020 · PMID 32463169

Abstract summary (English) BACKGROUND: Postpartum abdominal changes represent a major esthetic concern affecting women. As the abdomen stretches during pregnancy and some of the muscles lose tone, there is an increased skin laxity and a loss of abdominal elasticity. As a result, the abdomen becomes saggy.

Journal Article

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tier_other Low-temperature atmospheric plasma increases the expression of anti-aging genes of skin cells without causing cellular damages. Archives of dermatological research · 2012 · PMID 22773133

Abstract summary (English) Efforts to employ various types of plasma in the field of skin care have increased consistently because it can regulate many biochemical reactions that are normally unaffected by light-based therapy. One method for skin rejuvenation adopted a high-temperature plasma generator to remove skin epithelial cells. In this case, the catalyzing effects of the plasma were rarely used due to the high temperature.

Journal Article, Research Support, Non-U.S. Gov't

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Suggested interpretation

Limited evidence

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