GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Lifting / Laxity · Striae distensae

Microneedling RF evidence for Striae distensae

B 57.7 / 100 Supported 3 RCT/meta · 1 clinical/observational · 0 case · 8 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2021 Last 5 years 62% Positive results 50% Korea/Asia 2

Known in Korea as

실펌포텐자버츄RF아그네스프로파운드

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Comparing fractional microneedle radiofrequency and fractional CO2 laser for striae distensae treatment: a systematic review and meta-analysis. Lasers in medical science · 2024 · PMID 39516426

Abstract summary (English) Striae distensae (SD) are a prevalent dermatological concern of women and approximately 90% of pregnant women experience these stretch marks. Fractional microneedle radiofrequency (FMR) and fractional CO2 laser (FCL) have gained substantial attention in the treatment of SD. In clinical studies, a clear superiority between FMR and FCL treatments is not found due to limited studies and sample sizes.

Journal Article, Systematic Review, Meta-Analysis, Comparative Study

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tier1 Microneedling Therapy for Striae Distensae: Systematic Review and Meta-Analysis. Aesthetic plastic surgery · 2024 · PMID 38509316

Abstract summary (English) INTRODUCTION: Striae distensae (SD), linear scars of derma, caused by disproportionate skin stretching, which indicates a cosmetic problem and even endangers individuals' psychosocial health. Microneedling, representing a relatively new procedural therapy, has shown brightening but diverse results in the remedy of SD. Our study systematically investigates and further evaluates the efficacy of microneedling for SD.

Systematic Review, Journal Article, Meta-Analysis

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tier1 Comparative study of treatment for striae alba stage striae gravidarum: 1565-nm non-ablative fractional laser versus fractional microneedle radiofrequency. Lasers in medical science · 2021 · PMID 33411130

Abstract summary (English) Striae gravidarum is a common dermatologic condition for females caused by multiple factors during pregnancy. It remains a therapeutic challenge especially in the striae alba (SA) stage, generating psychological and emotional distress to those affected. This study aims to compare the efficacy and safety of 1565-nm non-ablative fractional laser (NAFL) and fractional microneedle radiofrequency (MRF) for treatment of...

Journal Article, Randomized Controlled Trial

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tier2 A comparison study of the 0.1% tretinoin cream versus fractional microneedle radiofrequency combination with fractional CO2 laser for the treatment of striae alba in Indonesian patients. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2021 · PMID 34519226

Abstract summary (English) Striae distensae (SD) are linear scar tissue in the dermis that arises from stretching the skin. There are two types of SD, striae rubrae and striae albae (SA) which is marked with a line hypopigmentation that cause a psychological problem, especially in the high skin type. The standard therapy is a 0.1% tretinoin cream, but it takes a long time to reach the collagen so it needs invasive measures to reach these...

Comparative Study, Journal Article

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tier0_review New Progress in Therapeutic Modalities of Striae Distensae. Clinical, cosmetic and investigational dermatology · 2022 · PMID 36213315

Abstract summary (English) Striae distensae (stretch marks/striae gravidarum) is one of the common cosmetic problems that can cause psychological distress and anxiety to patients due to its disfiguring damage, especially for women. The etiology of striae distensae is currently unknown, and risk factors include low maternal age, family history of stretch marks, excessive weight gain during pregnancy, and high neonatal weight. This article...

Journal Article, Review

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tier_other Dermoscopy and VISIA imager evaluations of non-insulated microneedle radiofrequency versus fractional CO2 laser treatments of striae distensae. Journal of the European Academy of Dermatology and Venereology : JEADV · 2020 · PMID 32030833

Abstract summary (English) BACKGROUNDS: Striae distensae (SD) has a known psychological impact due to the resulting cosmetic disfigurement. Many treatment modalities have been used over the years, but no standard interventions or evaluation methods have been proposed to date. OBJECTIVE: We compared the efficacy and safety of non-insulated microneedle radiofrequency (NIMRF) and fractional CO2 laser treatments of SD by objective...

Journal Article

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tier_other Promising Option for Treatment of Striae Alba: Fractionated Microneedle Radiofrequency in Combination with Fractional Carbon Dioxide Laser. Dermatology research and practice · 2016 · PMID 27069471

Abstract summary (English) Background. A consistent treatment has not been proposed for treatment of Striae Alba (SA). The present study was designed to compare the fractionated microneedle radiofrequency (FMR) alone and in combination with fractional carbon dioxide laser (FMR + CO2) in the treatment of SA.

Journal Article

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tier_other Clinical improvement of striae distensae in Korean patients using a combination of fractionated microneedle radiofrequency and fractional carbon dioxide laser. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2013 · PMID 23895146

Abstract summary (English) BACKGROUND: Striae distensae are dermal scars with flattening and atrophy of the epidermis. OBJECTIVE: To evaluate the efficacy and safety of combination therapy with fractionated microneedle radiofrequency (RF) and fractional carbon dioxide (CO2) laser in the treatment of striae distensae. MATERIALS AND METHODS: Thirty patients (30 female; mean age 33, range 21-51, Fitzpatrick skin type IV) with moderate to severe...

Journal Article

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Suggested interpretation

Limited evidence

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