Mesotherapy skin cocktail evidence for Androgenetic alopecia - male

Abstract summary (English) BACKGROUND: Treatment options for male androgenetic alopecia (AGA) range from pharmacologic agents-such as minoxidil, finasteride, and dutasteride-to newer procedural and experimental therapies. AIMS: We determined the relative effect of the various dosages and administrative routes of minoxidil, finasteride and dutasteride through network meta-analysis (NMA) of relevant outcome measures. METHODS: We conducted a...

Comparative Study, Journal Article, Network Meta-Analysis, Systematic Review

Abstract summary (English) Mesotherapy is a technique by which lower doses of therapeutic agents and bioactive substances are administered by intradermal injections to the skin. Through intradermal injections, mesotherapy can increase the residence time of therapeutic agents in the affected area, thus allowing for the use of lower doses and longer intervals between sessions which may in turn improve the treatment outcome and patient...

Systematic Review, Journal Article

Abstract summary (English) Telogen effluvium is one of the most common forms of diffuse, non-scarring hair loss for which patients present for clinical evaluation. It is usually a reactive and reversible disorder. Identifying and correcting the underlying cause is the most important component in management, yet there is always a need for therapeutic options.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND AND OBJECTIVE: As a minimally invasive procedure, mesotherapy has been used in the cosmetic field for half a century and gets favorable results in fat reduction, facial rejuvenation, and hair regrowth. So far, it has achieved some exciting progression in pattern hair loss (PHL), which bothers plenty of people and has cost billion dollars searching for more effective treatment. The aim of this study is to...

Systematic Review, Journal Article

Abstract summary (English) BACKGROUND: Cosmetic procedures for antiaging carry inherent risks of adverse events. One that has not yet been well characterized is transitory or permanent alopecia. This is attributable to numerous mechanisms including pressure, ischemia, inflammation, and necrosis.

Journal Article, Systematic Review

Abstract summary (English) Pain evaluation during local injections is a complex process. Injections cause patient's distress, especially when the target is a sensitive area such as scalp. Nonpharmacological methods as vibration before and during the procedure have been used to reduce pain.

Journal Article, Randomized Controlled Trial

Abstract summary (English) Female androgenetic alopecia is one cause of alopecia in women, although the ideal treatment for this condition remains far from defined. The objective of this study was to evaluate the efficacy and safety of intradermal injections with 0.5% minoxidil for the management of female androgenetic alopecia in a randomized, placebo-controlled trial. A total of 54 women diagnosed with female androgenetic alopecia were...

Journal Article, Randomized Controlled Trial

Abstract summary (English) The efficacy of mesotherapy in the treatment of female pattern hair loss (FPHL) has not yet been evaluated. Aim of the study was to compare the initial efficacy and safety of mesotherapy containing nutritional supplements to topical minoxidil 5% solution in FPHL. 30 patients with FPHL were randomly classified into two equal groups: Group A applied minoxidil 5% lotion twice daily; Group B was injected with...

Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) INTRODUCTION: Androgenetic alopecia (AGA) is a common condition in transgender and gender-diverse (TGD) individuals and may have an important psychosocial impact by exacerbating gender dysphoria and impairing quality of life. Hair loss patterns and treatment considerations in this population are influenced by genetic predisposition, cumulative androgen exposure, and the use of gender-affirming hormone therapy...

Journal Article, Review

Abstract summary (English) Patterned hair loss (PHL) is a severe hair condition that affects both sexes. Mesotherapy is a treatment that involves microinjecting medications and/or vitamins into the middle layer of the skin. Mesotherapy reduces systemic adverse effects by delivering drugs directly to the hair follicle, increasing local bioavailability while lowering systemic exposure.

Journal Article, Review