GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Hair Restoration · Androgenetic alopecia - female

Mesotherapy skin cocktail evidence for Androgenetic alopecia - female

C 48.1 / 100 Supported 8 RCT/meta · 0 clinical/observational · 12 case · 38 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2022 Last 5 years 50% Positive results 50%

Known in Korea as

콜라겐 부스터

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Current application of mesotherapy in pattern hair loss: A systematic review. Journal of cosmetic dermatology · 2022 · PMID 35253335

Abstract summary (English) BACKGROUND AND OBJECTIVE: As a minimally invasive procedure, mesotherapy has been used in the cosmetic field for half a century and gets favorable results in fat reduction, facial rejuvenation, and hair regrowth. So far, it has achieved some exciting progression in pattern hair loss (PHL), which bothers plenty of people and has cost billion dollars searching for more effective treatment. The aim of this study is to...

Systematic Review, Journal Article

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tier1 Intradermal injections with 0.5% minoxidil for the treatment of female androgenetic alopecia: A randomized, placebo-controlled trial. Dermatologic therapy · 2020 · PMID 33269529

Abstract summary (English) Female androgenetic alopecia is one cause of alopecia in women, although the ideal treatment for this condition remains far from defined. The objective of this study was to evaluate the efficacy and safety of intradermal injections with 0.5% minoxidil for the management of female androgenetic alopecia in a randomized, placebo-controlled trial. A total of 54 women diagnosed with female androgenetic alopecia were...

Journal Article, Randomized Controlled Trial

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tier1 Comparing the Efficacy of Mesotherapy to Topical Minoxidil in the Treatment of Female Pattern Hair Loss Using Ultrasound Biomicroscopy: A Randomized Controlled Trial. Acta dermatovenerologica Croatica : ADC · 2019 · PMID 31032783

Abstract summary (English) The efficacy of mesotherapy in the treatment of female pattern hair loss (FPHL) has not yet been evaluated. Aim of the study was to compare the initial efficacy and safety of mesotherapy containing nutritional supplements to topical minoxidil 5% solution in FPHL. 30 patients with FPHL were randomly classified into two equal groups: Group A applied minoxidil 5% lotion twice daily; Group B was injected with...

Comparative Study, Journal Article, Randomized Controlled Trial

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tier0_review Minimally invasive procedures for the management of female pattern hair loss. Journal of cosmetic dermatology · 2022 · PMID 35713007

Abstract summary (English) BACKGROUND: Female Pattern Hair Loss (FPHL) is one of the most common types of hair loss in women. It is characterized by progressive follicular miniaturization leading to diffuse hair thinning over the midfrontal scalp with a negative impact on quality of life. Pharmacological treatments are commonly used, and hair follicle transplantation is an option for those cases with adequate donor area.

Journal Article, Review

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tier3 Persistent Alopecic Patches Following Dutasteride Mesotherapy for Female Androgenetic Alopecia: A Case Series. Journal of drugs in dermatology : JDD · 2026 · PMID 41779759

Abstract summary (English) BACKGROUND: Androgenetic alopecia (AGA) is the most common cause of hair loss. To minimize systemic adverse effects of 5-alpha-reductase inhibitors, dutasteride mesotherapy has gained popularity. Although generally considered safe, alopecia at injection sites has been increasingly reported.

Journal Article, Case Reports

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tier3 Hair loss at injection sites of mesotherapy for alopecia. Journal of cosmetic dermatology · 2017 · PMID 28160387

Abstract summary (English) BACKGROUND: The side effects of mesotherapy for treatment of various forms of alopecia are often underreported, while scientific data for its efficacy are severely lacking. OBJECTIVE: To demonstrate the late onset side effects of mesotherapy for alopecia. METHODS: Three patients with androgenetic alopecia showed hair loss after previously uneventful mesotherapy sessions up to 1 year.

Case Reports, Journal Article

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tier_other Injectable platelet-rich fibrin for treatment of female pattern hair loss. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2024 · PMID 38989555

Abstract summary (English) This case series evaluated use of injectable platelet rich fibrin (termed i-PRF+) for the treatment of female pattern hair loss (FPHL). Eleven individuals underwent 3-monthly intradermal injections of i-PRF+ using a mesotherapy gun. The mean number of hair follicles containing hairs per unit area improved at 3- and 6-months follow-up (p < .001), and all participants had a negative hair pull test.

Journal Article

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tier_other Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label, Non-randomized, Prospective Study. Cureus · 2023 · PMID 37818523

Abstract summary (English) Background Many patients with polycystic ovary syndrome (PCOS) exhibit female pattern hair loss (FPHL). A more advanced, efficient, and suitable therapeutic approach is required to effectively manage FPHL in patients with PCOS. Aim Dr.

Journal Article

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tier_other Mesotherapy With Dutasteride for Androgenetic Alopecia: A Retrospective Study in Real Clinical Practice. Journal of drugs in dermatology : JDD · 2022 · PMID 35816059

Abstract summary (English) BACKGROUND: 5-alpha inhibitors are an effective treatment for androgenetic alopecia. Mesotherapy with dutasteride has been proposed as an effective method to improve hair loss and reducing systemic absorption. OBJECTIVE: The main objective was to describe the safety profile of mesotherapy with dutasteride in real clinical practice in a large cohort of patients with androgenetic alopecia.

Journal Article

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tier_other Prescribing Habits for Androgenic Alopecia Among Dermatologists in Spain in 2017: A Cross-Sectional Study. Actas dermo-sifiliograficas · 2018 · PMID 29656764

Abstract summary (English) BACKGROUND: Topical minoxidil and oral finasteride are the only drugs approved for the treatment of androgenetic alopecia (AGA) in Spain. However, the management of this condition is highly variable because numerous treatments are used off-label. The main aim of this study was to describe the prescribing habits of dermatologists in Spain for male AGA (MAGA) and female AGA (FAGA).

Journal Article

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Suggested interpretation

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