GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Inflammatory / Specialty · Atopic dermatitis

LED phototherapy evidence for Atopic dermatitis

D 34.6 / 100 Supported 3 RCT/meta · 4 clinical/observational · 1 case · 30 total
Insufficient evidence

There is not yet enough PubMed evidence for this combination. The procedure exists, but research on this indication may be scarce.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2016 Last 5 years 31% Positive results 50% Negative results 2 Korea/Asia 2

Known in Korea as

스킨아우라

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Synergistic Effects of the 308-nm Excimer Light and Topical Calcipotriol for the Treatment of Chronic Hand Eczema: A Randomized Controlled Study. Dermatology (Basel, Switzerland) · 2020 · PMID 31982887

Abstract summary (English) BACKGROUND: Though topical corticosteroid is a standard treatment for chronic hand eczema (CHE), it can cause many adverse effects. Topical calcipotriol and monochromatic 308-nm excimer light (MEL) are new alternative therapies for several dermatoses, including CHE. OBJECTIVE: This study aims to compare the efficacy of the combination of MEL and topical calcipotriol versus topical calcipotriol alone.

Journal Article, Randomized Controlled Trial

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tier1 The diabetic foot and leg: combined He-Ne and infrared low-intensity lasers improve skin blood perfusion and prevent potential complications. A prospective study on 30 Egyptian patients. Lasers in medical science · 2011 · PMID 21455785

Abstract summary (English) The objective of this study was to examine skin blood flow in diabetic patients having disease-related skin lesions, and to evaluate possible improvement imposed by low-intensity laser therapy (LILT) as a new treatment modality. Thirty patients (in addition to 15 controls receiving conventional treatment = group II and 15 others receiving no treatment = group III) having diabetes-related skin lesions were tested for...

Journal Article, Randomized Controlled Trial

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tier2 A pilot study showing pulsed-dye laser treatment improves localized areas of chronic atopic dermatitis. Clinical and experimental dermatology · 2008 · PMID 18201257

Abstract summary (English) BACKGROUND: Eczematous skin changes overlying port-wine stains have been reported to improve with pulsed-dye laser (PDL) treatment. However, PDL has not as yet been evaluated for the treatment of atopic dermatitis (AD; eczema). AIM: To evaluate in a controlled trial the effects and safety of PDL treatment in children with AD who had chronic localized lesions.

Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't

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tier2 Efficacy of monochromatic excimer light (308 nm) in the treatment of atopic dermatitis in adults and children. Photomedicine and laser surgery · 2008 · PMID 18248156

Abstract summary (English) OBJECTIVE: To demonstrate the efficacy of light produced by a 308 nm xenon-chloride monochromatic excimer light (MEL) in the treatment of localized lesions of atopic dermatitis (AD) in adults and in children. BACKGROUND DATA: The 308-nm excimer light has been reported to be safe and effective in the treatment of chronic skin diseases, although the range of potential applications has not been fully explored. METHODS:...

Clinical Trial, Journal Article

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tier2 Cutaneous immunological activation elicited by a low-fluence pulsed dye laser. The British journal of dermatology · 2005 · PMID 16280023

Abstract summary (English) BACKGROUND: Three years ago, the nonablative wrinkle reduction laser (a 585-nm laser, Chromogenex V3; Chromogenex Light Technologies, Llanelli, U.K.) was developed, and there have already been several reports about its clinical effectiveness. The Chromogenex V3 laser has also been reported to be effective in treating acne and atopic dermatitis. These results suggest that the Chromogenex V3 laser has some...

Clinical Trial, Journal Article

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tier0_review Illuminating microflora: shedding light on the potential of blue light to modulate the cutaneous microbiome. Frontiers in cellular and infection microbiology · 2024 · PMID 38660491

Abstract summary (English) Cutaneous diseases (such as atopic dermatitis, acne, psoriasis, alopecia and chronic wounds) rank as the fourth most prevalent human disease, affecting nearly one-third of the world's population. Skin diseases contribute to significant non-fatal disability globally, impacting individuals, partners, and society at large. Recent evidence suggests that specific microbes colonising our skin and its appendages are often...

Journal Article, Review, Research Support, Non-U.S. Gov't

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tier0_review Advances in phototherapy for psoriasis and atopic dermatitis. Expert review of clinical immunology · 2019 · PMID 31575297

Abstract summary (English) Introduction: Phototherapy has long been used for the treatment of inflammatory skin diseases, such as psoriasis and atopic dermatitis. The most frequent treatment approach utilizes ultraviolet (UV) light, however, recently, different lasers and low-level light therapies (LLLT) emitting wavelengths in the spectrum of the visible light have also been tried for the treatment of inflammatory skin diseases with...

Journal Article, Research Support, Non-U.S. Gov't, Review, Video-Audio Media

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tier0_review Pityriasis Alba--Common Disease, Enigmatic Entity: Up-to-Date Review of the Literature. Pediatric dermatology · 2015 · PMID 26477326

Abstract summary (English) Pityriasis alba (PA) is a skin disorder that affects children and adolescents. Although it is common worldwide, its incidence is markedly higher in darker skin phototypes. Its characteristic features include an extended, multistage course and spontaneous remissions and recurrences.

Journal Article, Review

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tier0_review Role of phototherapy in patients with skin of color. Seminars in cutaneous medicine and surgery · 2011 · PMID 22123415

Abstract summary (English) Phototherapy has proven to be one of the most versatile and effective treatment options for a variety of inflammatory and pigmentary skin diseases. However, the use of these treatment modalities in patients of color requires some special considerations. The modality chosen, the dosing of the treatment and duration of treatment are all issues to be considered for patients of color treated with ultraviolet...

Journal Article, Research Support, Non-U.S. Gov't, Review

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tier0_review [The excimer laser in dermatology and esthetic medicine]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2004 · PMID 14749862

Abstract summary (English) First reports about the use of the excimer laser in dermatology date back to 1997. It is seen as an improvement on conventional phototherapy and photochemotherapy because of the lower cumulative UV-dose involved, the shorter time frame required for treatment and the option of targeting individual lesions without affecting the surrounding healthy skin. In addition to the indications of psoriasis vulgaris, vitiligo...

English Abstract, Journal Article, Review

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Suggested interpretation

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