Hair Removal · Hirsutism / PCOS
Laser hair removal alexandrite ndyag evidence for Hirsutism / PCOS
There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Includes meta-analysis/SR Median year 2009 Last 5 years 12% Positive results 38% Negative results 9 Korea/Asia 11
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier1 Laser and Light-Based Therapies for Hirsutism Management in Women With Polycystic Ovarian Syndrome: A Systematic Review.
Abstract summary (English) IMPORTANCE: Hirsutism represents a significant concern for women with polycystic ovary syndrome (PCOS), with deleterious psychological effects warranting acknowledgment and a clear imperative to provide effective management. To our knowledge, this is the first review to exclusively examine the effectiveness of laser and light-based therapies in addressing hirsutism in women with PCOS. OBJECTIVE: To synthesize the...
Journal Article, Systematic Review
View on PubMedtier1 Adding Combined Oral Contraceptives or Metformin to Laser Treatment in Polycystic Ovarian Syndrome Hirsute Patients.
Abstract summary (English) BACKGROUND: Hirsutism is estimated to affect 10% to 20% of females, provoking significant psychological damage and social embarrassment. Polycystic ovary syndrome is a major cause of hirsutism. AIM: Assessing the impact of adding combined oral contraceptives (COCs) or metformin to laser hair removal on the quality of life of polycystic ovarian syndrome (PCOS) patients with hirsutism.
Journal Article, Randomized Controlled Trial
View on PubMedtier1 A randomized clinical trial on the comparison between hair shaving and snipping prior to laser hair removal sessions in women suffering from hirsutism.
Abstract summary (English) BACKGROUND AND OBJECTIVES: Hirsutism or excess hair growth is a common dermatological problem in females, affecting up to 10% of females worldwide. We aimed this study to compare the two hair-shortening methods shaving vs. snipping among hirsute women regarding the outcome of the therapy and also the paradoxical hypertrichosis phenomenon (terminal hair regrowth) 6 months after the final therapy session.
Comparative Study, Journal Article, Randomized Controlled Trial
View on PubMedtier1 The effect of topical finasteride 0.5% on the outcome of diode laser therapy in the treatment of excess facial hairs in the women with hirsutism.
Abstract summary (English) OBJECTIVE: To determine the effects of topical finasteride 0.5% on the results of diode laser therapy in the treatment of hirsutism. METHODS: This double-blind, placebo-controlled, clinical trial study was conducted at a private clinic in Babol, Iran, between June 2012 and July 2013, and comprised women with idiopathic hirsutism. A diode laser (810nm) treatment was applied monthly for 6 months with an extra session...
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Adjuvant eflornithine to maintain IPL-induced hair reduction in women with facial hirsutism: a randomized controlled trial.
Abstract summary (English) BACKGROUND: Photoepilation is the treatment of choice for hair removal in patients with hirsutism, but it remains a challenge to prevent regrowth of hairs. OBJECTIVES: The objective of this study was to investigate whether topical eflornithine maintains hair reduction in hirsute patients after cessation of intense pulsed light (IPL) therapy. METHODS: A randomized, split-face, single-blinded controlled trial on...
Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't
View on PubMedtier1 The Effect of Topical Glycerol Trinitrate on Laser-Aided Facial Hair Removal: A Triple-Blinded Randomized Clinical Trial.
Abstract summary (English) OBJECTIVE: Our purpose in this study was to assess the effect of topical glyceryl trinitrate on the efficacy of long-term white hair removal aided by laser therapy in hirsute women. BACKGROUND DATA: Nitric oxide (NO) induces vasorelaxation and augmented perfusion when released from endothelial cells or from an alternatively provided exogenous source. Separately, vascular endothelial growth factor (VEGF)-mediated...
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Hirsutism: an evidence-based treatment update.
Abstract summary (English) BACKGROUND: Hirsutism has a relatively high prevalence among women. Depending upon societal and ethnic norms, it can cause significant psychosocial distress. Importantly, hirsutism may be associated with underlying disorders and co-morbidities.
Journal Article, Systematic Review
View on PubMedtier1 A randomized double blind, vehicle controlled bilateral comparison study of the efficacy and safety of finasteride 0.5% solution in combination with intense pulsed light in the treatment of facial hirsutism.
Abstract summary (English) OBJECTIVE: We sought to determine whether topical finasteride can enhance the efficacy of intense pulsed light hair removal. MATERIALS AND METHODS: An intense pulsed light (IPL) treatment with radiofrequency (RF) was performed every four weeks, resulting in up to three sessions, and again at the end of the study - 6 months after the start of the experiment. Each patient also applied either finasteride or placebo...
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Comparison between sequentional treatment with diode and alexandrite lasers versus alexandrite laser alone in the treatment of hirsutism.
Abstract summary (English) Laser systems that are commonly used for the treatment of hirsutism include the ruby laser (694 nm), the diode laser (800 nm), the alexandrite laser (755 nm) and the Nd:YAG laser (1084 nm). The diode laser and alexandrite laser are considered effective in treatment of hirsutism in dark-skinned patients. The response of hairs to these laser systems is variable and not complete.
Comparative Study, Journal Article, Randomized Controlled Trial
View on PubMedtier1 Successful white hair removal with combined coloring and intense pulsed Light (IPL): a randomized clinical trial.
Abstract summary (English) OBJECTIVE: The purpose of this study was to introduce adjunct therapy to intense pulsed light (IPL) and to assess it in terms of safety, expense, feasibility, and efficacy. BACKGROUND DATA: Currently there is no satisfactory, efficient method for long-term white hair removal. METHODS: We conducted a randomized clinical trial of hirsute patients with excessive white hair on the chin and cheeks.
Journal Article, Randomized Controlled Trial
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