GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Hair Removal · Facial / upper lip hair

Laser hair removal alexandrite ndyag evidence for Facial / upper lip hair

C 49.6 / 100 Supported 15 RCT/meta · 10 clinical/observational · 7 case · 72 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2010 Last 5 years 24% Positive results 40% Negative results 4 Korea/Asia 6

Known in Korea as

제모클라리티레이저제모클라리티2레이저 제모겨드랑이 제모아포지 플러스젠틀맥스 프로제모 레이저제모아포지플러스 남성제모

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Efficacy of lasers and light sources in long-term hair reduction: a systematic review. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2022 · PMID 35634805

Abstract summary (English) Laser and light-based devices provide scope for long-term "hair-removal" however, there is limited evidence supporting their long-term efficacy. This study aimed to assess the long-term efficacy of laser and light-based "hair-removal" devices, taking into account variations in body site-specific variations in hair growthcycles. A systematic review of randomized controlled trials (RCTs) with follow-up periods greater...

Systematic Review, Journal Article

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tier1 Efficacy and safety of mascara dyeing as an adjunct to Alexandrite and Nd:YAG laser applications for removing thin and white-colored facial and axillary hair. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2016 · PMID 27762642

Abstract summary (English) INTRODUCTION: There is no satisfactory and efficient method for long-term removal of white-colored and thin hair. METHODS: We conducted a randomised clinical trial of hirsute patients with excessive white and/or thin hair on the face and/or axilla. In Group I (n: 16), the facial hair on one side of the face was painted with a black eyelash mascara immediately before Nd:YAG laser and the other half was only treated...

Journal Article, Randomized Controlled Trial

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tier1 Adjuvant eflornithine to maintain IPL-induced hair reduction in women with facial hirsutism: a randomized controlled trial. Journal of the European Academy of Dermatology and Venereology : JEADV · 2015 · PMID 26507926

Abstract summary (English) BACKGROUND: Photoepilation is the treatment of choice for hair removal in patients with hirsutism, but it remains a challenge to prevent regrowth of hairs. OBJECTIVES: The objective of this study was to investigate whether topical eflornithine maintains hair reduction in hirsute patients after cessation of intense pulsed light (IPL) therapy. METHODS: A randomized, split-face, single-blinded controlled trial on...

Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier1 The Effect of Topical Glycerol Trinitrate on Laser-Aided Facial Hair Removal: A Triple-Blinded Randomized Clinical Trial. Photomedicine and laser surgery · 2015 · PMID 26580831

Abstract summary (English) OBJECTIVE: Our purpose in this study was to assess the effect of topical glyceryl trinitrate on the efficacy of long-term white hair removal aided by laser therapy in hirsute women. BACKGROUND DATA: Nitric oxide (NO) induces vasorelaxation and augmented perfusion when released from endothelial cells or from an alternatively provided exogenous source. Separately, vascular endothelial growth factor (VEGF)-mediated...

Journal Article, Randomized Controlled Trial

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tier1 Topical liposomal Rose Bengal for photodynamic white hair removal: randomized, controlled, double-blind study. Journal of drugs in dermatology : JDD · 2014 · PMID 24719063

Abstract summary (English) BACKGROUND: Blond and white hair removal by laser is a complicated task with weak satisfactory results due to the deficiency in laser-absorbing chromophore. OBJECTIVE: To investigate if repetitive sessions of photodynamic therapy (PDT) using external application of liposomal Rose bengal (RB) photosensitizer followed by intense pulsed light (IPL) exposure enables removal of gray and white hair. MATERIALS AND METHODS:...

Journal Article, Randomized Controlled Trial

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tier1 A randomized double blind, vehicle controlled bilateral comparison study of the efficacy and safety of finasteride 0.5% solution in combination with intense pulsed light in the treatment of facial hirsutism. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2012 · PMID 22658123

Abstract summary (English) OBJECTIVE: We sought to determine whether topical finasteride can enhance the efficacy of intense pulsed light hair removal. MATERIALS AND METHODS: An intense pulsed light (IPL) treatment with radiofrequency (RF) was performed every four weeks, resulting in up to three sessions, and again at the end of the study - 6 months after the start of the experiment. Each patient also applied either finasteride or placebo...

Journal Article, Randomized Controlled Trial

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tier1 Skin characteristics of Chinese men and their beard removal habits. The British journal of dermatology · 2012 · PMID 22385031

Abstract summary (English) BACKGROUND: Grooming habits of men in China have some marked differences from those in other areas in the world, with a high percentage of men resorting to shaving with an electric razor. This is influenced by multiple factors, such as a lower facial hair growth density concentrated in a small area around the mouth. Further, there is limited knowledge and misconceptions around the alleged negative skin effects of...

Comparative Study, Journal Article, Randomized Controlled Trial

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tier1 Male skin and ingredients relevant to male skin care. The British journal of dermatology · 2012 · PMID 22385030

Abstract summary (English) Male skin care needs are heavily influenced by the need to remove facial hair on a regular basis. Facial skin issues associated with poor hair removal approaches are common and include razor burn and irritation. This paper evaluates current research on shaving technology and how careful ingredient selection can contribute to male skin health.

Journal Article, Randomized Controlled Trial, Review

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tier1 Successful white hair removal with combined coloring and intense pulsed Light (IPL): a randomized clinical trial. Photomedicine and laser surgery · 2011 · PMID 21740277

Abstract summary (English) OBJECTIVE: The purpose of this study was to introduce adjunct therapy to intense pulsed light (IPL) and to assess it in terms of safety, expense, feasibility, and efficacy. BACKGROUND DATA: Currently there is no satisfactory, efficient method for long-term white hair removal. METHODS: We conducted a randomized clinical trial of hirsute patients with excessive white hair on the chin and cheeks.

Journal Article, Randomized Controlled Trial

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tier1 A randomised, split-face comparison of facial hair removal with the alexandrite laser and intense pulsed light system. Lasers in surgery and medicine · 2007 · PMID 18081147

Abstract summary (English) INTRODUCTION: Despite the high incidence of polycystic ovary syndrome (PCOS) in women attending for facial hair removal there are few studies looking specifically at this patient group. We carried out a split-face study directly comparing the efficacy of a 3 milliseconds pulse duration alexandrite laser with the Lumina IPL system in 38 women with PCOS. MATERIALS AND METHODS: Each patient underwent six treatments...

Journal Article, Randomized Controlled Trial

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