GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Hair Removal · Axilla hair removal

Laser hair removal alexandrite ndyag evidence for Axilla hair removal

B 58.2 / 100 Supported 25 RCT/meta · 23 clinical/observational · 14 case · 80 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2013 Last 5 years 16% Positive results 44% Negative results 7 Korea/Asia 9

Known in Korea as

제모클라리티레이저제모클라리티2레이저 제모겨드랑이 제모아포지 플러스젠틀맥스 프로제모 레이저제모아포지플러스 남성제모

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Efficacy and Pain Tolerance of Alexandrite Laser Hair Removal at Different Stages of the Menstrual Cycle. Aesthetic surgery journal · 2024 · PMID 38394336

Abstract summary (English) BACKGROUND: Several different parameters play a role in the transition of hair follicles to the anagen phase, with the role of androgens, progesterone, and estrogen hormones and receptors being significant. OBJECTIVES: The effectiveness of laser hair removal (LHR) and pain tolerance during procedure were investigated during 3 different phases of the menstrual cycle. METHODS: Forty-eight axillae were randomly divided...

Journal Article, Randomized Controlled Trial

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tier1 Attempted treatment of primary axillary hyperhidrosis with one session of either Neodymium YAG laser or Intense Pulsed Light: A within patient randomized trial of treated versus untreated contralateral axilla. Lasers in surgery and medicine · 2023 · PMID 37313834

Abstract summary (English) BACKGROUND: Primary axillary hyperhidrosis (PAH) affects 1-5% of the world's population who has an unmet need for improved treatments. The heating of sweat glands with specific microwave therapy has shown promising results, yet, treatment with widely available devices such as long-pulsed Neodymium Yttrium Aluminum Garnet (Nd:YAG) lasers, diode lasers or Intense Pulsed Light (IPL) may serve as pragmatic alternatives....

Randomized Controlled Trial, Case Reports, Research Support, Non-U.S. Gov't, Journal Article

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tier1 Comparative effectiveness of ice packs versus topical lidocaine-prilocaine mixture for pain control in laser hair removal of the axilla: A rater-blinded randomized controlled trial. Journal of the American Academy of Dermatology · 2022 · PMID 36410628

Abstract summary (English) BACKGROUND: Laser hair removal is associated with moderate acute pain. OBJECTIVE: To compare effectiveness of ice pack to topical lidocaine-prilocaine for pain reduction during axillary laser hair removal. METHODS: Participants were randomly assigned to receive topical anesthetic to one axilla and ice packs to the other before each of 3, monthly 810 nm diode laser sessions.

Randomized Controlled Trial, Journal Article

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tier1 Efficacy of lasers and light sources in long-term hair reduction: a systematic review. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2022 · PMID 35634805

Abstract summary (English) Laser and light-based devices provide scope for long-term "hair-removal" however, there is limited evidence supporting their long-term efficacy. This study aimed to assess the long-term efficacy of laser and light-based "hair-removal" devices, taking into account variations in body site-specific variations in hair growthcycles. A systematic review of randomized controlled trials (RCTs) with follow-up periods greater...

Systematic Review, Journal Article

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tier1 Pathophysiology, clinical findings, and management of Fox-Fordyce disease: A systematic review. Journal of cosmetic dermatology · 2021 · PMID 33817950

Abstract summary (English) BACKGROUND: Fox-Fordyce (FFD), also known as apocrine military, is an uncommon chronic inflammation of the apocrine sweat glands. It is characterized by pruritic, papular eruptions in apocrine-gland-bearing regions. FFD was described a century ago, but the exact pathogenesis of the disease and the management are not well understood.

Journal Article, Systematic Review

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tier1 Comparison of efficacy and safety of a novel 755-nm diode laser with conventional 755-nm alexandrite laser in reduction of axillary hairs. Lasers in medical science · 2019 · PMID 31278429

Abstract summary (English) The aim of this study was to compare the efficacy and safety of a novel diode system emitting 755 nm wavelength with conventional 755 nm alexandrite laser in skin types III and IV. It was a randomized, right-left comparison, assessor-blind, clinical study. Sixteen female volunteers age 29.52 ± 9.52 were randomly assigned to receive six treatment sessions using 755 nm diode laser on one axilla and 755 nm alexandrite...

Comparative Study, Journal Article, Randomized Controlled Trial

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tier1 Efficacy and safety of mascara dyeing as an adjunct to Alexandrite and Nd:YAG laser applications for removing thin and white-colored facial and axillary hair. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2016 · PMID 27762642

Abstract summary (English) INTRODUCTION: There is no satisfactory and efficient method for long-term removal of white-colored and thin hair. METHODS: We conducted a randomised clinical trial of hirsute patients with excessive white and/or thin hair on the face and/or axilla. In Group I (n: 16), the facial hair on one side of the face was painted with a black eyelash mascara immediately before Nd:YAG laser and the other half was only treated...

Journal Article, Randomized Controlled Trial

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tier1 A comparative clinical study of different hair removal procedures and their impact on axillary odor reduction in men. Journal of cosmetic dermatology · 2015 · PMID 26663394

Abstract summary (English) BACKGROUND: Axillary hair can influence the development of underarm odor in men. OBJECTIVE: To compare different hair removal procedures and their impact on the effectiveness of standard soap washing (SW) in reducing male axillary odor. METHODS: The axillae of healthy Caucasian males (N = 30; 18-48 years of age) were randomized in a non-crossover, split body design.

Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier1 Fixed, low radiant exposure vs. incremental radiant exposure approach for diode laser hair reduction: a randomized, split axilla, comparative single-blinded trial. Journal of the European Academy of Dermatology and Venereology : JEADV · 2015 · PMID 26299540

Abstract summary (English) BACKGROUND: Diode lasers are the most commonly used treatment modalities for unwanted hair reduction. Only a few controlled clinical trials but not a single randomized controlled trial (RCT) compared the impact of various laser parameters, especially radiant exposure, onto efficacy, tolerability and safety of laser hair reduction. OBJECTIVE: To compare the safety, tolerability and mid-term efficacy of fixed, low and...

Comparative Study, Journal Article, Randomized Controlled Trial

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tier1 The effect of axillary hair on surgical antisepsis around the shoulder. Journal of shoulder and elbow surgery · 2014 · PMID 25487899

Abstract summary (English) BACKGROUND: Infection after shoulder surgery can have devastating consequences. Recent literature has implicated Propionibacterium acnes as a causative agent for postoperative shoulder infections. Axillary hair removal has been suggested as a method for infection prevention, although data quantifying its effect on the bacterial load around the shoulder are lacking.

Journal Article, Randomized Controlled Trial

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Suggested interpretation

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