Ionzyme iontophoresis sonophoresis evidence for Active inflammatory acne

Abstract summary (English) BACKGROUND: The selective photothermolysis of sebaceous follicles with topically applied gold nanoparticles, followed by light exposure, shows good efficacy for acne treatment. Methods such as sonophoresis or CO₂ fractional laser can help to deliver gold nanoparticles efficiently. Additionally, ethosomes are introduced to enhance the skin penetration of gold nanoparticles.

Journal Article, Randomized Controlled Trial

Abstract summary (English) The acid skin surface pH has antimicrobial activities. Increased growth of Propionibacterium acnes contributes to the pathogenesis of acne. Therefore, the pH of inflammatory acne lesions was determined prior to and after lesional acidification employing Herpifix (Courage + Khazaka, Cologne, Germany), a microphoretic system.

Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) Increased sebum production is one of causes of Acne. This is under androgen control. Acne subjects have significantly greater sebum production than subjects without Acne and this relates to Acne's severity.

Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article

Abstract summary (English) BACKGROUND: Common treatment of atrophic acne scars consists of invasive methods such as dermabrasion, chemopeeling, or implantation of bovine collagen. In our study a new noninvasive treatment method consisting of local iontophoresis is demonstrated. Local iontophoresis was performed with either estriol--a mainly topically active estrogen--or with tretinoin.

Clinical Trial, Controlled Clinical Trial, Journal Article

Abstract summary (English) INTRODUCTION: Scarring is a common but difficult to manage consequence of acne vulgaris. The intricate balance between the degradation of collagen and its inhibition is disturbed during the formation of acne scars. We mostly rely on invasive, non-topical modalities for the treatment of acne scars which may not be indicated in all patients.

Journal Article, Review

Abstract summary (English) OBJECTIVE: Iontophoresis is defined as the use of electric current to drive molecules across cell membranes through an electrolyte solution. In therapeutic context, it is used to facilitate the administration of bioactive substances, either systemically or locally. The technique presents various advantages and that is why it has been successfully used by a plethora of medical sciences.

Journal Article, Review

Abstract summary (English) This article reviewed some of the more common diseases of the skin appendages that are encountered in medicine: hyperhidrosis, acne, AA, FPHL, AGA, and TE. The pathophysiology behind the conditions and their treatments were discussed so that the clinician can make logical therapeutic choices for their affected patients.

Journal Article, Review

Abstract summary (English) Acne vulgaris is a prevalent dermatological disorder associated with inflammation and sebaceous gland hyperactivity. Conventional therapies, including topical and systemic agents, are limited by side effects, antimicrobial resistance, and frequent relapse. Light-absorbing gold microparticles activated by long-pulsed 1064 nm Nd:YAG laser therapy represent a novel, non-invasive approach targeting sebaceous glands.

Case Reports, Journal Article

Abstract summary (English) Background: Despite the numerous treatments available for acne vulgaris, not all are efficacious, and many patients experience psychological distress and various side effects from medications used to treat this condition. The objective of this study was to develop a new surgical technique for the treatment of acne. Methods: This surgical technique utilizes tweezers to widen the hair follicle to...

Case Reports, Journal Article

Abstract summary (English) PURPOSE: Several treatment options for acne vulgaris are limited by their associated adverse effects. An innovative approach involves introducing light-absorbing nanoparticles into sebaceous follicles before destroying the follicles using selective photothermolysis. We aimed to investigate efficient methods for introducing gold and platinum nanoparticles into sebaceous follicles and to identify suitable laser...

Journal Article