Hyperbaric oxygen evidence for Chronic wound / diabetic ulcer

Abstract summary (English) BACKGROUND: Sleep disturbances are common after traumatic brain injury (TBI), yet there are no guidelines specific to non-pharmacologic management in this population. OBJECTIVE: To evaluate whether adults with post-TBI sleep disturbances benefit from commonly described non-pharmacologic therapies - cognitive behavioural therapy (CBT) (including for insomnia, CBT-I), hyperbaric oxygen (HBO2), blue-wavelength light...

Journal Article, Systematic Review, Meta-Analysis

Abstract summary (English) Hyperbaric oxygen therapy (HBOT) involves inhaling 100% oxygen at pressures exceeding one atmosphere within a chamber. It is used across several specialties and has been proposed as an adjunct in burn management to enhance healing and improve outcomes. Despite increasing interest, evidence supporting its efficacy in burn care remains inconsistent, with no clear consensus in practice.

Journal Article, Systematic Review

Abstract summary (English) INTRODUCTION: The primary objective of this review was to evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) in the treatment of inner ear decompression sickness (IEDCS). Secondary objectives were to summarise the diver characteristics, HBOT parameters and outcome measures. METHODS: All descriptive observational study designs including case series and individual case reports involving divers suffering...

Journal Article, Systematic Review, Review

Abstract summary (English) BACKGROUND: Radiotherapy (RT) is a cornerstone in cancer management, but late radiation tissue injury (LRTI) remains a relevant clinical issue, affecting approximately 5% of patients and significantly impacting quality of life. Hyperbaric oxygen therapy (HBOT), by enhancing tissue oxygenation and promoting neovascularization, has been proposed both as a treatment for RT-induced toxicities and as a potential...

Journal Article, Systematic Review, Review

Abstract summary (English) Background and Objectives: To evaluate and synthesize evidence on the independent clinical effectiveness, safety, and applicability of Negative Pressure Wound Therapy (NPWT) and Hyperbaric Oxygen Therapy (HBOT) in diabetic foot ulcers (DFUs), and to determine whether current evidence allows for a direct comparison between both interventions: NPWT and HBOT are widely advanced therapies for DFUs. Although both...

Journal Article, Systematic Review

Abstract summary (English) OBJECTIVE: To assess the efficacy of hyperbaric oxygen therapy (HBOT) in facilitating recovery from exercise-induced muscle injury and soreness. DATA SOURCES: China Knowledge Network, Embase, Web of Science, Cochrane Library, PubMed, and Scopus database inception until September 28, 2024. STUDY SELECTION: A randomized controlled trial to assess the effects on patients with exercise-induced muscle damage and soreness.

Journal Article, Systematic Review, Meta-Analysis, Review

Abstract summary (English) Traumatic brain injury (TBI) is a series of pathophysiological disorders of the brain resulting from direct or indirect impact on the head. The cognitive impairments associated with TBI significantly affect the quality of life and pose public health challenges. However, effective treatment options remain limited, and existing therapies often involve prolonged treatment durations and restricted efficacy.

Journal Article, Systematic Review, Research Support, Non-U.S. Gov't

Abstract summary (English) BACKGROUND: Head and neck cancer (HNC), most of which are squamous cell carcinomas, is the seventh most common cancer worldwide. Radiotherapy is a standard treatment for HNC but may lead to late complications and severe complications like osteoradionecrosis (ORN) and impaired wound healing due to tissue hypoxia. Hyperbaric oxygen therapy (HBOT) has shown promise in ameliorating these late radiation effects.

Journal Article, Systematic Review

Abstract summary (English) OBJECTIVES: Hyperbaric Oxygen (HBO₂) Therapy has been associated with some risks and adverse events. Previous studies examining otologic complications from HBO₂ therapy vary in their reported incidence of adverse events. This study aims to systematically review the otologic complications associated with HBO₂ therapy and investigate contributing risk and protective factors.

Systematic Review, Journal Article

Abstract summary (English) OBJECTIVE: This study aimed to comprehensively compare the efficacy of 12 interventions for diabetic foot ulcer (DFU) using a network meta-analysis (NMA). METHODS: The NMA was conducted by PRISMA guidelines, and the protocol was registered in PROSPERO (CRD42023461811). PubMed, Web of Science, Cochrane Library, and Embase databases were systematically searched from inception to September 2023.

Comparative Study, Journal Article, Network Meta-Analysis, Systematic Review