Lifting / Laxity · Submental / neck laxity
HIFU lifting evidence for Submental / neck laxity
There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Includes meta-analysis/SR Median year 2019 Last 5 years 28% Positive results 44%
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier1 Prospective, Single-arm, Split-face Pain Management Evaluation of Nitrous Oxide System During Micro-Focused Ultrasound With Visualization.
Abstract summary (English) BACKGROUND: Although micro-focused ultrasound with visualization (MFU-V) has great cosmetic results, patients can be hesitant or decline the treatment due to the pain experienced during the treatment. The primary objective is to assess the efficacy of pain management of the nitrous oxide system during MFU-V treatment. The secondary objectives include patient satisfaction and efficacy on reducing facial laxity and...
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Systematic review and meta-analysis of safety and efficacy of high-intensity focused ultrasound (HIFU) for face and neck rejuvenation.
Abstract summary (English) High-intensity focused ultrasound (HIFU) is widely used for skin rejuvenation and tightening. The aim of this study was to determine the safety and efficacy of HIFU for face and neck rejuvenation. A systematic search of peer reviewed articles published before December 2017 was performed using Medline, Web of Science, and Scopus databases.
Journal Article, Meta-Analysis, Systematic Review
View on PubMedtier1 A Randomized, Split-Face, Evaluator-Blind Clinical Trial Comparing Monopolar Radiofrequency Versus Microfocused Ultrasound With Visualization for Lifting and Tightening of the Face and Upper Neck.
Abstract summary (English) BACKGROUND: Over the past decade, 2 major modalities for noninvasive skin tightening have emerged: monopolar capacitive-coupled radiofrequency (MRF) and microfocused ultrasound with visualization (MFU-V). Up to date, no comparative clinical trials have been performed. OBJECTIVE: To compare the efficacy and safety of MRF versus MFU-V for the lifting and tightening of the face and neck.
Journal Article, Randomized Controlled Trial
View on PubMedtier1 A Randomized Evaluator-Blinded Trial Comparing Subsurface Monopolar Radiofrequency With Microfocused Ultrasound for Lifting and Tightening of the Neck.
Abstract summary (English) BACKGROUND: Both subsurface monopolar radiofrequency (SMRF) and microfocused ultrasound with visualization (MFU-V) have demonstrated the ability to lift and tighten the neck. No head-to-head comparison study exists of these 2 technologies. OBJECTIVE: To compare the efficacy and safety of SMRF and MFU-V for the lifting and tightening of neck.
Comparative Study, Journal Article, Randomized Controlled Trial
View on PubMedtier2 Clinical Trial Evaluating the Long-Term Efficacy of Microfocused Ultrasound With Visualization for Décolleté Rejuvenation.
Abstract summary (English) Previous studies have demonstrated the beneficial effects of microfocused ultrasound with visualization (MFU-V) for treating chest wrinkles; however, those studies followed subjects for only 180 days. The objective of the following study was to assess the long-term effects of MFU-V for the treating chest wrinkles. Each subject was treated with 4-4.5 mm, 7-3.0 mm, and 10-1.5 mm transducers.
Clinical Trial, Journal Article
View on PubMedtier2 Intense focused ultrasound for neck and lower face skin tightening a prospective study.
Abstract summary (English) BACKGROUND: Intense focused ultrasound (IFUS) is a Nonablative skin tightening technology with good safety profile, but limited efficacy. Most clinical studies have been performed to evaluate the efficacy of the Ulthera IFUS (Ulthera, Mesa, AZ) in treating redundant skin. OBJECTIVE: To report our experience with Doublo IFUS (Doublo™, HIRONIC Co.) for treating neck and lower face laxity.
Journal Article, Observational Study
View on PubMedtier2 High-Intensity Focused Ultrasound: A Satisfactory Noninvasive Procedure for Neck Rejuvenation.
Abstract summary (English) BACKGROUND: High-intensity focused ultrasound (HIFU) is an advanced technology that has been developed in response to the growing demand for noninvasive face rejuvenation. OBJECTIVES: The aim of this study was to evaluate the rejuvenation effects, patient satisfaction, and safety of HIFU treatment of the neck in a European population. METHODS: This was a prospective study of 20 patients.
Clinical Trial, Journal Article, Video-Audio Media
View on PubMedtier2 Synergistic effect of high-intensity focused ultrasound and low-fluence Q-switched Nd:YAG laser in the treatment of the aging neck and décolletage.
Abstract summary (English) High-intensity focused ultrasound (HIFU) is regarded as an effective skin-lifting device; however, literature regarding treatment of the aging neck and décolletage with HIFU is scarce. Our study aimed to evaluate the efficacy of combination with HIFU and low-fluence Q-switched Nd:YAG (LQSNY) laser on the aging neck and décolletage. Nineteen women were assessed.
Clinical Trial, Journal Article
View on PubMedtier2 Evaluation of Micro-Focused Ultrasound for Lifting and Tightening Neck Laxity.
Abstract summary (English) BACKGROUND: A novel device using micro-focused ultrasound with high-resolution ultrasound visualization (MFU-V) produces non-invasive lifting and tightening of lax skin on the face and neck when treatment is delivered at a single focal depth (Ulthera® System; Ulthera, Inc., Mesa, AZ).
OBJECTIVE: The following study was performed to test the hypothesis that customized application of MFU-V at two focal depths...
Evaluation Study, Journal Article
View on PubMedtier0_review Patient satisfaction of microfocused ultrasound treatments on the face and neck laxity: A narrative review.
Abstract summary (English) BACKGROUND: Microfocused ultrasound with visualization (MFU-V) delivers focused ultrasound energy to heat tissue and has emerged as a fast and effective noninvasive method for treating skin laxity. After obtaining approval in 2009 by the Food and Drug Administration, satisfactory feedback was recorded using several scoring systems for MFU-V treatment for facial and neck laxity. AIM: To evaluate the efficacy and...
Journal Article, Review
View on PubMedPersonalized evidence report
Tell us more about your concern
and the Glass Lab bot will build a personalized report for you.
Based on the HIFU lifting · Submental / neck laxity information on this page, we'll email you an evidence summary tailored to your skin condition and treatment stage.