GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Lifting / Laxity · Brow ptosis

HIFU lifting evidence for Brow ptosis

C 39.5 / 100 Supported 1 RCT/meta · 0 clinical/observational · 0 case · 5 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2020 Last 5 years 43% Positive results 57% Korea/Asia 2

Known in Korea as

울핏슈링크울쎄라리프테라리프테라2바디 울쎄라울쎄라 프라임초음파 리프팅슈링크 유니버스울쎄라피 프라임

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Ultrasound rejuvenation for upper facial skin: A randomized blinded prospective study. Journal of cosmetic dermatology · 2024 · PMID 39034504

Abstract summary (English) BACKGROUND: Growing demand for facial rejuvenation drives advancements in these therapies, including laser, radiofrequency, and focused ultrasound, alongside thermal stimulation adjuncts. These methods, known for stimulating collagen regeneration, skin tightening, and lifting, have gained popularity due to their minimal side effects, low trauma, and high safety, demonstrating favorable outcomes in clinical practice....

Journal Article, Randomized Controlled Trial

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tier0_review Rejuvenation of the Upper Face and Periocular Region: Combining Neuromodulator, Facial Filler, Laser, Light, and Energy-Based Therapies for Optimal Results. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2016 · PMID 27128248

Abstract summary (English) BACKGROUND: The upper face and periocular region is a complex and dynamic part of the face. Successful rejuvenation requires a combination of minimally invasive modalities to fill dents and hollows, resurface rhytides, improve pigmentation, and smooth the mimetic muscles of the face without masking facial expression. METHODS: Using review of the literature and clinical experience, the authors discuss our strategy...

Journal Article, Review

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tier_other Efficacy and safety of microfocused ultrasound for temporary eyebrow lift and glabellar wrinkle reduction. Lasers in medical science · 2025 · PMID 39920474

Abstract summary (English) Microfocused ultrasound (MFU) is a noninvasive treatment method that is widely used for skin tightening. In this study, we investigated the efficacy and safety of a novel MFU device for temporary eyebrow lifting and glabellar wrinkle reduction. In this prospective, single-center, single-arm, and open-label study, 38 patients were enrolled.

Journal Article

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tier_other The Efficacy and Safety of Synchronized Radiofrequency and High Intensity Facial Electrical Stimulation in Improving Facial Skin Laxity and Quality in Asians. Lasers in surgery and medicine · 2025 · PMID 39800907

Abstract summary (English) BACKGROUND: Noninvasive aesthetic procedures for facial rejuvenation are gaining popularity. Conventional treatments, such as radiofrequency (RF) and high-intensity focused ultrasound (HIFU), primarily improve skin quality but do not address the deeper musculoaponeurotic structures that affect facial laxity. A novel approach that delivers synchronized RF with high intensity facial electrical stimulation (HIFES)...

Journal Article

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tier_other The efficacy of macro-focused ultrasound in the treatment of upper facial laxity: A pilot study. Journal of cosmetic dermatology · 2020 · PMID 32539204

Abstract summary (English) BACKGROUND: Recently, macro-focused ultrasound (MFU) has become a popular noninvasive esthetic treatment for facial laxity. However, there are no studies done that evaluated the use of MFU with a 2.0 mm transducer for upper facial lifting. AIMS: To evaluate the efficacy and safety of MFU with a 2.0 mm transducer in the treatment of upper facial laxity in Thai patients.

Journal Article

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tier_other Quantitative Analysis of Face and Neck Skin Tightening by Microfocused Ultrasound With Visualization in Asians. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2017 · PMID 28945618

Abstract summary (English) BACKGROUND: Previous studies of microfocused ultrasound with visualization (MFU-V) on facial and neck laxity were largely based on masked physician assessments, histological analysis, and safety profile. More quantitative studies are needed. OBJECTIVE: To evaluate the 800 treatment lines of MFU-V on skin tightening effect of face and neck in Asians using 2 quantitative analysis systems at 0, 90, and 180 days after...

Journal Article

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tier_other Long-term Efficacy of Micro-focused Ultrasound with Visualization for Lifting and Tightening Lax Facial and Neck Skin Using a Customized Vectoring Treatment Method. The Journal of clinical and aesthetic dermatology · 2016 · PMID 27047630

Abstract summary (English) BACKGROUND: Micro-focused ultrasound with visualization has been cleared by the United States Food and Drug Administration to noninvasively lift the eyebrow, lift submental and neck tissue, and improve lines and wrinkles of the décolleté. OBJECTIVE: The objective of this prospective, open-label pilot study was to evaluate the efficacy and safety of patient-specific, customized micro-focused ultrasound with...

Journal Article

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Suggested interpretation

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