GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Lifting / Laxity · Decollete laxity

HA skin booster evidence for Decollete laxity

B 54.3 / 100 Supported 1 RCT/meta · 1 clinical/observational · 0 case · 3 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2023 Last 5 years 100% Positive results 100%

Known in Korea as

레티젠필메드물광주사스킨바이브스킨바이브 (booster)

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 A hyaluronic acid-based micro-filler improves superficial wrinkles and skin quality: a randomized prospective controlled multicenter study. The Journal of dermatological treatment · 2023 · PMID 37577796

Abstract summary (English) BACKGROUND: NCTF®135HA is a bio-revitalizing solution containing hyaluronic acid designed to compensate for skin dehydration, fatigue, and fine wrinkles associated with endogenous and environmental aging. METHODS: We conducted a randomized, active-controlled study to evaluate the efficacy and tolerability of NCTF®135HA injections on the face (crow's feet), neck, and décolleté regions. Subjects were randomly assigned...

Randomized Controlled Trial, Multicenter Study, Journal Article

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tier2 Clinical and Biometric Assessment of a Hyaluronic Acid-Based Skin Booster for Face, Neck and Décolleté Rejuvenation: A Prospective Study. Journal of cosmetic dermatology · 2025 · PMID 41243364

Abstract summary (English) BACKGROUND: Hyaluronic acid based skinboosters present a low rheological profile that allows for even distribution throughout the dermis and focuses on improving skin's overall quality. Scientific efforts are ongoing with the aim of developing optimal skinboosters that meet specific clinical requirements and satisfactory overall results. OBJECTIVE: Assess clinically the efficacy and safety of a newly developed...

Journal Article, Clinical Trial

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tier_other High-velocity pneumatic injection of non-crosslinked hyaluronic acid for skin regeneration and scar remodeling: A retrospective analysis of 115 patients. Journal of cosmetic dermatology · 2021 · PMID 33580573

Abstract summary (English) BACKGROUND: Pneumatic-assisted high velocity jet injections are an alternative method for intradermal delivery of hyaluronic acid (HA) and demonstrated efficacy in dermal thickening and scar remodeling with minimal side effects. AIMS: We aimed to investigate the clinical efficacy comparing non-crosslinked HA (NCL-HA) and crosslinked HA (CL-HA) for aesthetic skin concerns. METHODS: We retrospectively analyzed charts...

Journal Article

View on PubMed

Suggested interpretation

Limited evidence

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