GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Acne / Scar / Texture · Atrophic acne scar - rolling

Fractional picosecond resurfacing evidence for Atrophic acne scar - rolling

B Supported 1 RCT/meta · 0 clinical/observational · 0 case · 6 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade is an expert appraisal of the actual studies — their design, quality and on-topic relevance — while direction is a separate signal showing how those studies assess effectiveness.

Median year 2022 Last 5 years 67% Korea/Asia 3

Known in Korea as

피코프락셀

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Comparison of the fractionated Nd: YAG 1064-nm picosecond laser with holographic optics and the fractional CO2 laser in atrophic acne scar treatment: a prospective, randomized, split-face study. International journal of dermatology · 2024 · PMID 38924534

Abstract summary (English) KEY POINT: The 1064-nm picosecond laser with holographic optics demonstrated significant efficacy in treating atrophic acne scars. BACKGROUND: Picosecond lasers with fractionated optics have enabled the development of a breakthrough skin rejuvenation method. The authors compared the fractionated, non-ablative neodymium-doped yttrium aluminum garnet 1064-nm picosecond laser with holographic optics and the fractional...

Journal Article, Randomized Controlled Trial, Comparative Study

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tier_other Comparison of 1064-nm Nd:YAG picosecond laser using fractional micro-lens array vs. ablative fractional 2940-nm Er:YAG laser for the treatment of atrophic acne scar in Asians: a 20-week prospective, randomized, split-face, controlled pilot study. Frontiers in medicine · 2023 · PMID 38034535

Abstract summary (English) BACKGROUND: The 1064-nm Nd:YAG picosecond lasers using fractional micro-lens array (P-MLA) was a promising therapy for skin resurfacing. However, no studies have compared P-MLA with ablative fractional 2940-nm Er:YAG lasers (AF-Er) in the treatment of atrophic acne scars. OBJECTIVES: To evaluate the efficacy and safety of P-MLA and AF-Er for the treatment of atrophic acne scars.

Journal Article

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tier_other Efficacy of a one-session fractional picosecond 1064-nm laser for the treatment of atrophic acne scar and enlarged facial pores. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2022 · PMID 35318885

Abstract summary (English) A picosecond-domain laser reportedly elicits positive treatment outcomes for acne scar and enlarged pores, but multiple sessions are often required. We sought to evaluate the efficacy of one-session fractional picosecond 1064-nm laser in treating atrophic acne scar and conspicuous pores. Fifty-nine acne scar patients with skin phototypes III and IV were treated with picosecond 1064-nm laser with microlens array...

Journal Article

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tier_other The Efficacy and Safety of Fractional 1064 nm Nd:YAG Picosecond Laser Combined With Intense Pulsed Light in the Treatment of Atrophic Acne Scar: A Split-Face Study. Lasers in surgery and medicine · 2021 · PMID 34082477

Abstract summary (English) BACKGROUND AND OBJECTIVES: To evaluate the efficacy and safety of fractional 1064 nm Nd:YAG picosecond laser combined with intense pulsed light (IPL) in the treatment of atrophic acne scar with post-inflammatory erythema (PIE). © 2021 Wiley Periodicals LLC. STUDY DESIGN/MATERIALS AND METHODS: Seventeen patients received five sessions of treatment at weeks 0, 4, 8, 12, 16 and were followed up at week 28.

Journal Article, Research Support, Non-U.S. Gov't

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tier_other Objective and Long-Term Evaluation of the Efficacy and Safety of a 1064-nm Picosecond Laser With Fractionated Microlens Array for the Treatment of Atrophic Acne Scar in Asians. Lasers in surgery and medicine · 2020 · PMID 33326626

Abstract summary (English) BACKGROUND AND OBJECTIVE: Fractional 1064-nm picosecond-domain laser has recently been utilized for the treatment of atrophic acne scars and showed promising results. However, data on the safety and efficacy of this procedure in dark-skinned patients are limited. This prospective, self-controlled study was conducted to objectively evaluate the safety and efficacy of a 1064-nm picosecond laser coupled with a...

Journal Article

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tier_other Noninvasive Atrophic Acne Scar Treatment in Asians With a 755-nm Picosecond Laser Using A Diffractive Optic Lens-A Retrospective Photographic Review. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2019 · PMID 30234649

Abstract summary (English) BACKGROUND: The diffractive lens of the picosecond laser is relatively new, and there are few reports on its efficacy in treating atrophic acne scars, especially in Asian populations. OBJECTIVE: Evaluating the efficacy of diffractive lens 755-nm picosecond laser for atrophic acne scar treatment in Asians. PATIENTS AND METHODS: Forty-two patients who were treated for facial atrophic acne scars at a private...

Journal Article

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Suggested interpretation

Limited evidence

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