Cryolipolysis body contouring evidence for Thigh fat
This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Median year 2015 Last 5 years 18% Positive results 55% Negative results 3
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier1 Cooling of Lower Extremity Muscles According to Subcutaneous Tissue Thickness.
Abstract summary (English) CONTEXT: When using an ice bag, previous researchers recommended cooling times based on the amount of subcutaneous tissue. Unfortunately, many clinicians are unaware of these recommendations or whether they can be applied to other muscles. OBJECTIVE: To examine if muscles of the lower extremity cool similarly based on recommended cooling times.
Journal Article, Randomized Controlled Trial
View on PubMedtier2 Aesthetic Improvement With Topical Body Skin Treatment as a Complement to Cryolipolysis.
Abstract summary (English) BACKGROUND: A firming and toning cosmetic body lotion (FTB) was developed to target key pathways relevant to body skin health and rejuvenation that may complement the improvements observed after noninvasive body contouring (NIBC). A pilot study explored the efficacy and tolerability of FTB as an adjunct to cryolipolysis. METHODS: An open-label, single-site, single-arm, 12-week study enrolled subjects aged 20 to 65...
Clinical Study, Journal Article
View on PubMedtier2 From Esthetic Medicine to Optimizing Reconstructive Outcome: A Feasibility Trial on Secondary Refinement of Fasciocutaneous Anterolateral Thigh Flaps with Cryolipolysis.
Abstract summary (English) BACKGROUND: Free adipocutaneous anterolateral thigh (ALT) flaps have evolved as workhorse flaps to reconstruct complex, multicompound defects. While coverage is safely achieved, flaps may remain bulky. As a standard of care, flaps are refined with liposuction, partial excision, or combination of both.
Clinical Trial, Journal Article
View on PubMedtier2 A Prospective, Comparative Study (before and after) for the Evaluation of Cryothermogenesis' Efficacy in Body Contouring: Abdomen and Saddlebags.
Abstract summary (English) BACKGROUND: Cryolipolysis is a noninvasive method that allows selective reduction of adipose tissue. The aim of the present study was to evaluate the efficacy of cryothermogenesis, the repetitive applications of cryotherapy, in body contouring of the abdomen and saddlebag areas. METHODS: Thirty participants were included in the study.
Clinical Trial, Comparative Study, Journal Article
View on PubMedtier2 The efficacy of cryolipolysis treatment on arms and inner thighs.
Abstract summary (English) Cryolipolysis has emerged as a new non-invasive body contouring method using controlled cooling to selectively destroy fat cells. Previous studies demonstrated the safety and efficacy of cryolipolysis for the reduction of localized subcutaneous fat on abdomen and flanks. Recently, the new flat cup vacuum applicator has been developed to treat localized subcutaneous fat on arms and inner thighs.
Clinical Trial, Journal Article
View on PubMedtier2 Cryolipolysis for safe and effective inner thigh fat reduction.
Abstract summary (English) BACKGROUND AND OBJECTIVES: While cryolipolysis initially received FDA clearance for fat reduction in the abdomen and flanks, there was significant interest in non-surgical fat reduction for other sites, such as the inner and outer thighs. This article reports the results of an inner thigh study which contributed to FDA clearance of cryolipolysis for treatment of thighs. STUDY DESIGN/MATERIAL AND METHODS: A flat cup...
Clinical Trial, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't
View on PubMedtier2 Cryolipolysis conformable-surface applicator for nonsurgical fat reduction in lateral thighs.
Abstract summary (English) BACKGROUND: Vacuum applicators have been effective for cryolipolysis of the abdomen, flanks, inner thighs, back, chest, and arms. However, the lateral thighs have not been easily treated because fat from this area cannot be easily drawn into a vacuum cup. OBJECTIVES: The authors investigated the safety and efficacy of a prototype applicator for treatment of "nonpinchable" fat in the lateral thighs.
Clinical Trial, Journal Article, Multicenter Study
View on PubMedtier2 Fat reduction in the inner thigh using a prototype cryolipolysis applicator.
Abstract summary (English) BACKGROUND: Previous clinical studies have investigated cryolipolysis for noninvasive reduction of fat in abdomens, outer thighs, flanks, and backs. This study investigated feasibility of cryolipolysis for inner thigh treatment. OBJECTIVE: This pilot study evaluated a cryolipolysis flat cup vacuum applicator for treatment of inner thigh fat.
Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't
View on PubMedtier2 Anthropometric characteristics and sex influence magnitude of skin cooling following exposure to whole body cryotherapy.
Abstract summary (English) This study explored whether anthropometric measures influence magnitude of skin cooling following exposure to whole body cryotherapy (WBC). Height, weight, body fat percentage, and lean mass were measured in 18 male and 14 female participants. Body surface area, body surface area to mass ratio, body mass index, fat-free mass index, and fat mass index were calculated.
Clinical Trial, Journal Article
View on PubMedtier2 Subcutaneous adipose tissue thickness alters cooling time during cryotherapy.
Abstract summary (English) OBJECTIVE: To determine if differing subcutaneous adipose thickness alters the treatment duration required to produce a standard cooling effect during cryotherapy. DESIGN: A 4-group, between-groups comparison in which the independent variable was skinfold thickness (0-10mm, 11-20mm, 21-30mm, 31-40mm) and the dependent variable was cooling time, defined as the treatment duration required to decrease intramuscular...
Comparative Study, Journal Article, Research Support, Non-U.S. Gov't
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