Cryolipolysis body contouring evidence for Abdominal fat
There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Includes meta-analysis/SR Median year 2019 Last 5 years 32% Positive results 62% Negative results 3 Korea/Asia 3
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier1 Evaluation of the Efficacy and Safety of Cryolipolysis in Reducing Local Adipose Tissue in Women-A Randomized Pilot Study.
Abstract summary (English) INTRODUCTION: Cryolipolysis was developed in 2007 as a method of reducing excessive adipose tissue using low temperatures. During the procedure, lipid crystallization occurs at temperatures much higher than the freezing point of water in the tissues. This is followed by the recruitment of macrophages, the number of which peaks at 4 weeks and disappears at about 3 months after treatment.
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Effects of cryolipolysis on subcutaneous adipose tissue of adult women: immunohistochemical analysis.
Abstract summary (English) BACKGROUND: The skin, the largest organ in the human body, is composed of complex layers that include subcutaneous adipose tissue. Understanding the characteristics of this skin structure is essential to optimize therapeutic interventions, such as cryolipolysis, aiming for more effective and personalized results. OBJECTIVE: To evaluate the immunohistochemical effects of skin tissue in adult women undergoing...
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Metabolic changes after nonsurgical fat removal: A dose response meta-analysis.
Abstract summary (English) BACKGROUND: Obesity-induced insulin resistance leads to the metabolic syndrome. Both bariatric surgery and surgical fat removal have been shown to improve metabolic health, but the metabolic benefits of nonsurgical fat removal remain uncertain. The aim of this paper is to establish whether nonsurgical fat removal exerts measurable, lasting metabolic benefits by way of changes to serum lipid profiles.
Meta-Analysis, Journal Article, Review
View on PubMedtier1 Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial.
Abstract summary (English) BACKGROUND AND OBJECTIVES: To investigate the adding effect of Cryolipolysis to a low-calorie diet program on lipid profile, liver enzymes, body mass index, waist-to-hip ratio, and volume reduction of subcutaneous fat tissue in central obese women. STUDY DESIGN/MATERIALS AND METHODS: Sixty central obese women were randomly divided into two equal groups. Women in the control group received prescribed low-calorie diet...
Journal Article, Randomized Controlled Trial
View on PubMedtier1 A randomized double-blind trial evaluating the efficacy and tolerability of topical body treatment with TriHex Technology® combined with abdomen cryolipolysis or radiofrequency procedures.
Abstract summary (English) BACKGROUND: Nonsurgical fat reduction procedures using cryolipolysis and radiofrequency are among the most popular noninvasive aesthetic procedures. In a previous study, TransFORM Body Treatment (TFB) with TriHex Technology® (ALASTIN® Skincare) improved the contour and reduced skin laxity following cryolipolysis of the arms. This product is formulated using a combination of peptides and other...
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Effects of cryolipolysis on lower abdomen fat thickness of healthy women and patient satisfaction: a randomized controlled trial.
Abstract summary (English) OBJECTIVE: To analyze the effects of cryolipolysis on the fat thickness of the lower abdomen of healthy women and patient's satisfaction. METHODS: Design and setting: a randomized controlled trial, with concealed allocation and blinded assessor. PARTICIPANTS: 34 healthy women between 18 and 48 years, skinfold in the lower abdomen ≥3cm, BMI between 18.5 and 27kg/m2, low level of physical activity, and no...
Journal Article, Randomized Controlled Trial
View on PubMedtier1 Cryolipolysis versus laser lipolysis on adolescent abdominal adiposity.
Abstract summary (English) BACKGROUND: Noninvasive body contouring is one of the fastest growing segments of the cosmetic aesthetic industry. There is increased public demand for procedures with fewer side effects and shorter recovery times. Cryolipolysis and Laser lipolysis have been used as treatments for localized body contouring.
Comparative Study, Journal Article, Randomized Controlled Trial
View on PubMedtier2 Enhancing the Appearance of the "Six-Pack" Muscles Using Cryolipolysis: A Safe and Effective Method.
Abstract summary (English) Many individuals desire a defined and athletic body with "six-pack" abdominal muscles, but even with a strict regimen of diet and exercise, this result is unattainable for many. Cryolipolysis is a noninvasive method of reducing the subcutaneous adipose tissues lying above the rectus abdominis muscles, enhancing the six-pack appearance. Eleven nonobese adults with an average body mass index of 22.5 kg/m2 were...
Clinical Trial, Journal Article
View on PubMedtier2 Cryolipolysis-induced abdominal fat change: Split-body trials.
Abstract summary (English) Cryolipolysis has been considered as a noninvasive alternative to surgical procedures for reducing subcutaneous fat without affecting the surrounding tissues. However, no clinical trial has investigated changes in the abdominal fat tissue by 12 weeks after cryolipolysis. Therefore, in this split-body trial, we explored whether a single session of unilateral cryolipolysis could change visceral and subcutaneous...
Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't
View on PubMedtier2 Feasibility Study of Electromagnetic Muscle Stimulation and Cryolipolysis for Abdominal Contouring.
Abstract summary (English) BACKGROUND: In addition to reducing subcutaneous fat for body contouring, some patients are interested in toning the underlying muscle layer. OBJECTIVE: This feasibility study evaluated the safety and efficacy of electromagnetic muscle stimulation (EMMS) alone, cryolipolysis alone, and cryolipolysis with EMMS for noninvasive contouring of abdomen. METHODS: Abdomens of 50 subjects were treated in a study with 3...
Clinical Trial, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't
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