Chemical peel evidence for Sebum / oily skin control

Abstract summary (English) BACKGROUND: Oily skin is characterized by excessive sebum production and increased activity of Cutibacterium acnes. AIMS: To evaluate the effects of mandelic acid exfoliation, microneedle mesotherapy with a sebum-regulating ampoule, and combination therapy on skin parameters and C. acnes activity in women with oily skin.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Photodamaged skin typically displays lentigines, actinic keratoses, wrinkles, and textural alteration. Chemical peeling has been used to treat these, but few controlled studies have been performed to determine its efficacy. OBJECTIVE: Our purpose was to compare the efficacy of a medium-depth chemical peel with and without tretinoin before and after treatment.

Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Hyperandrogenism and reduced skin autophagy have been implicated in the pathogenesis of adult female acne (AFA). Here, we tested whether a ready-to-use peel-off facial mask containing myoinositol (an androgen inhibitor) and trehalose-loaded liposomes (as activators of cutaneous autophagy) applied overnight every other day for 60 days can improve AFA. We also sought to investigate the molecular mechanisms...

Clinical Study, Journal Article

Abstract summary (English) BACKGROUND AND DESIGN: The aim of this study was to investigate the efficacy of 50% glycolic acid peeling performed at different phases of menstruation on acne. MATERIALS AND METHODS: This study included 30 patients with mild-to-moderate acne. Those with regular menstrual cycles and no history or laboratory evidence of hormonal pathology, hirsutism were selected.

Clinical Trial, Journal Article

Abstract summary (English) UNLABELLED: Pyruvic (alfa-keto acid) and salicylic (beta-hydroxy acid) acids are superficial peels frequently used in patients with acne vulgaris. AIM: The aim of the study was to compare the effect of 50% pyruvic and 30% salicylic peels on facial sebum secretion in patients with acne vulgaris, aged 13-30. MATERIAL AND METHODS: The level of secreted sebum was determined in 20 men and women.

Comparative Study, Journal Article, Research Support, Non-U.S. Gov't

Abstract summary (English) BACKGROUND: Glycolic acid and Jessner's solution are popular superficial chemical peel agents for the treatment of facial acne, and increased sebum secretion is one of the major aetiological factors of acne. OBJECTIVE: To compare the effects of 30% glycolic acid peels and Jessner's solution peels on sebum secretion in facial acne patients. METHODS: Thirty-eight patients with mild to moderate facial acne were...

Comparative Study, Journal Article, Research Support, Non-U.S. Gov't

Abstract summary (English) Chemical peels have been time-tested and are here to stay. Alpha-hydroxy peels are highly popular in the dermatologist's arsenal of procedures. Glycolic acid peel is the most common alpha-hydroxy acid peel, also known as fruit peel.

Journal Article, Review

Abstract summary (English) BACKGROUND: Superficial chemical peels offer therapeutic results in a convenient, affordable treatment. Many clinicians use these peels in the treatment of acne and acne-prone oily skin. OBJECTIVES: This article examines the evidence base that supports the widespread use of superficial peels in this setting.

Journal Article, Research Support, Non-U.S. Gov't, Review

Abstract summary (English) BACKGROUND: Acne is the most prevalent skin disorder in the United States, affecting up to 50 million people from all age groups. Treatment options include topical and systemic therapies. Limitation in many treatment options opens avenues for alternative therapies, such as chemical peeling.

Journal Article

Abstract summary (English) Background: Acne vulgaris is a common inflammatory disorder with significant clinical and psychosocial impacts. Medium-depth chemical peels are increasingly used to manage both active acne lesions and atrophic acne scars. This study aimed to quantitatively assess the clinical effectiveness of a novel multimodal medium-depth chemical peel regimen, yellow peel, in improving acne severity and scar depth, as well...

Journal Article