GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Body / Fat · Thigh fat

Bipolar multipolar RF contouring evidence for Thigh fat

C 48.4 / 100 Supported 2 RCT/meta · 6 clinical/observational · 0 case · 12 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2014 Last 5 years 17% Positive results 75% Negative results 2

Known in Korea as

GPC인모드코레지튠컬트라나노필로티세예핏-S써니리프팅코어스컬프트리플바디바디 인모드

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Use of Minimally Invasive Radiofrequency-Assisted Lipolysis as a Novel Treatment of Grade 2 and Grade 3 Cellulite. Plastic and reconstructive surgery · 2022 · PMID 35877933

Abstract summary (English) Cellulite is a common condition, and laxity in the superficial fascial system contributes significantly to its appearance in the thigh and buttock areas. Components of the superficial fascial system such as the fibrous septae and adipose tissue are targets for an effective treatment to improve the appearance of cellulite. This preliminary report demonstrates the use of radiofrequency-assisted lipolysis as a novel...

Journal Article, Randomized Controlled Trial

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tier1 The effectiveness of anticellulite treatment using tripolar radiofrequency monitored by classic and high-frequency ultrasound. Journal of the European Academy of Dermatology and Venereology : JEADV · 2011 · PMID 21692869

Abstract summary (English) BACKGROUND: Cellulite affects nearly 85% of the female population. Given the size of the phenomenon, we are continuously looking for effective ways to reduce cellulite. Reliable monitoring of anticellulite treatment remains a problem.

Journal Article, Randomized Controlled Trial

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tier2 Prospective Multicenter Clinical Trial of a Temperature-Controlled Subcutaneous Microneedle Fractional Bipolar Radiofrequency System for the Treatment of Cellulite. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2018 · PMID 30222637

Abstract summary (English) BACKGROUND: A bipolar fractional radiofrequency (RF) device was developed to generate cutaneous thermal injuries using a temperature-controlled microneedle electrode array. OBJECTIVE: Evaluate safety and efficacy of a novel subcutaneous microneedle RF for treatment of posterolateral thigh cellulite. METHODS: The study design was an institutional review board-approved multicenter clinical trial after a per-protocol...

Clinical Trial, Journal Article, Multicenter Study

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tier2 Reduction in adipose tissue volume using a new high-power radiofrequency technology combined with infrared light and mechanical manipulation for body contouring. Lasers in medical science · 2014 · PMID 24687404

Abstract summary (English) A growing patient demand for a youthful skin appearance with a favorable body shape has led to the recent development of new noninvasive body contouring techniques. We have previously demonstrated that the combination of bipolar radiofrequency (RF) and optical energies with tissue manipulation is an efficient reshaping modality. Here, we investigated the efficacy and safety of a new high-power version of this...

Clinical Trial, Journal Article, Multicenter Study

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tier2 A bipolar radiofrequency, infrared, vacuum and mechanical massage device for treatment of cellulite: a pilot study. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2011 · PMID 21981326

Abstract summary (English) Cellulite has a complex and multifactorial etiology. Synergistic action on treating cellulite has gained support in the treatment of cellulite. This study evaluated safety and efficacy of a bipolar radiofrequency, infrared, vacuum and mechanical massage device for cellulite treatment and reduction of body measures.

Clinical Trial, Journal Article

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tier2 Treatment of cellulite with a bipolar radiofrequency, infrared heat, and pulsatile suction device: a pilot study. Journal of cosmetic dermatology · 2006 · PMID 17716245

Abstract summary (English) BACKGROUND: Very few therapeutic options have proven effective in the treatment of cellulite. AIMS: To evaluate the effectiveness and adverse effects of a bipolar radiofrequency (RF), infrared (IR) heat and pulsatile suction device for the treatment of cellulite. METHODS: Twelve subjects were treated with the RF-light-based device.

Clinical Trial, Journal Article

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tier2 Cellulite treatment using a novel combination radiofrequency, infrared light, and mechanical tissue manipulation device. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2005 · PMID 16537213

Abstract summary (English) BACKGROUND: Most post-pubertal women exhibit cellulite, particularly in the thigh and buttock regions. The prevalence of cellulite has led to many attempts at treatment, including a variety of topical solutions, massage-based therapies, and surgical techniques--most with suboptimal clinical effects. The purpose of this controlled study was to evaluate a novel combination device involving radiofrequency, infrared...

Controlled Clinical Trial, Journal Article

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tier2 Transmembraneous irrigation of multipolar radiofrequency ablation catheters: induction of linear lesions encircling the pulmonary vein ostium without the risk of coagulum formation? Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2004 · PMID 15133356

Abstract summary (English) INTRODUCTION: Pulmonary vein (PV) isolation for the curative treatment of atrial fibrillation using conventional radiofrequency ablation (RF) catheters with the point by point technique is time consuming and carries a remaining risk for thrombembolic complications. AIMS OF THE STUDY: Aim of the present in vivo study was to evaluate feasibility and safety of a novel multipolar irrigated ablation catheter designed to...

Comparative Study, Evaluation Study, Journal Article

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tier_other Pilot Study: Endoscopic-assisted Plasma Radiofrequency Ablation: A Minimally Invasive Strategy for Extremity Lymphatic Malformations. Plastic and reconstructive surgery. Global open · 2025 · PMID 41142875

Abstract summary (English) BACKGROUND: Lymphatic malformations (LMs) of the extremities present a therapeutic challenge due to their diffuse infiltration of subcutaneous and deep fascial compartments, often complicated by previous treatment failures and high recurrence rates. METHODS: We conducted a pilot study to evaluate the feasibility and safety of a novel minimally invasive technique, endoscopic-assisted plasma radiofrequency ablation...

Journal Article

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tier_other Combination treatment with 150 W bipolar radiofrequency, infrared light, and ultrasound-induced lipolysis for thigh circumference reduction. Journal of cosmetic dermatology · 2020 · PMID 32558180

Abstract summary (English) BACKGROUND: A growing patient demand for a favorable body shape has led to the development of many new treatment modalities. Noninvasive devices were developed to improve body contour without physical intervention or scarring and with reduced downtime compared to surgical options such as liposuction. AIMS: This study examines combining radiofrequency, infrared light, and ultrasound-induced lipolysis for fat...

Journal Article

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